Nestoras Mathioudakis, MD MHS

06/09/2026

Yesterday, at the American Diabetes Association Scientific Session in New Orleans, I debated whether AI should be integrated into diabetes care now – and I argued yes.

AI is already changing what's possible: helping more people get screened for eye complications, supporting insulin decisions in places without specialist access, reducing the documentation burden that burns out so many diabetes providers, and extending care beyond the clinic visit with tools that support patients 24 hours a day.

Does AI have limitations? Absolutely — and those need to be taken seriously. But for the millions of Americans with diabetes who aren't getting the care they need today, waiting for perfect isn't a neutral choice.

Watch my ADA TV interview below and let me know what you think. Whether you're a patient, a caregiver, or a clinician — I'd love to hear your perspective. 👇

Artificial intelligence is already being used in diabetes preventio...

10/17/2025

I’m excited to announce the publication of our article in Clinical Diabetes, detailing a transformative state-wide initiative aimed at enhancing participation in the Diabetes Prevention Program ( ) and Diabetes Self-Management Education and Support ( ) services.

This 4-year initiative (2021-2024), funded by the Maryland Health Services Cost Review Commission (HSCRC), was a collaborative effort between Johns Hopkins Medicine and the University of Maryland Medical System, known as the Baltimore Metropolitan Diabetes Regional Partnership. In just the first year of the program, we saw significant increases in referrals and participation thanks to targeted investments and innovative quality improvement strategies!

It's important to note that participation in these evidence-based programs remains low across the U.S., not just in Maryland. We hope this initiative serves as a valuable playbook for other health systems and public health departments looking to expand vital services for individuals with and .

This article describes and evaluates a multipronged strategy to expand use of the Diabetes Prevention Program (DPP) and diabetes self-management education

10/29/2024

Excited to share findings from our recent study on the use of dexamethasone for COVID-19 in people with diabetes. Unlike in other hospitalized patients, we found that dexamethasone did not improve survival or recovery time for patients with diabetes. However, there was no higher risk of dangerous spikes in blood sugar levels.

For patients with more severe COVID-19 and diabetes, we actually saw slower recovery with dexamethasone, indicating the need for more research in this area.

AbstractBackground. Patients with diabetes have higher mortality from COVID-19 compared to the general population. Dexamethasone, a potent glucocorticoid u

08/21/2024

Grateful to TRIO-Maryland Chapter, Inc./ An Organ Transplant Support Group for the opportunity to discuss related diabetes and share insights on its diagnosis and management with such a dedicated group. It was a pleasure to highlight the impactful work being done through the JHM Diabetes Prevention & Education Program, especially in supporting patients with or undergoing solid organ transplantation. Programs like our and are vital in helping our transplant patients achieve better outcomes. Thank you for the warm reception and the chance to contribute to this important discussion. Johns Hopkins Brancati Center.

05/16/2024

🚀 Exciting News! 🚀

We've just published our clinical trial protocol comparing an AI-powered digital Diabetes Prevention Program ( ) with the standard human coach-based DPP. This study aims to see if artificial intelligence can provide a scalable, cost-effective way to combat prediabetes, a problem that affects more than 1 in 3 U.S. adults.

Enrollment of 368 participants complete, and results are expected in early 2025. Stay tuned for more updates!

Read more here: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-024-08177-8

JJHM Diabetes Prevention & Education ProgramJJohns Hopkins Brancati CenterRReading Hospital - Tower Health

Background Prediabetes is a highly prevalent condition that heralds an increased risk of progression to type 2 diabetes, along with associated microvascular and macrovascular complications. The Diabetes Prevention Program (DPP) is an established effective intervention for diabetes prevention. Howeve...

04/25/2024

🌟 Exciting News! 🌟 I had the honor of being a guest on the American Academy of Pain Medicine podcast to discuss the innovative world of in medicine.

Here are some key takeaways from our conversation:
- Overview of AI and Machine Learning: We explored how these technologies work and their integration into healthcare practices.

- Current Applications in Healthcare: We discussed real-world examples where AI is making strides, such as in diagnostics and personalized treatment plans, as well as helping make healthcare easier and more efficient (for example, helping clinicians with documentation).

-Areas of Uncertainty and Challenge: While AI offers tremendous potential, we also delved into the ethical and practical challenges it presents.

- Future Potential: The possibilities are vast, from revolutionizing patient care to enhancing disease prediction and management.

As we continue to embrace new technologies, it is important to consider how tools like AI can be used responsibly to improve health outcomes, particularly for those managing diabetes.

Let’s stay informed and optimistic about the future of healthcare technology!

👉 Listen to the full podcast here...

Join us for a riveting exploration into the rapidly evolving world of artificial intelligence (AI) in interdisciplinary pain medicine. This episode of the Pain Matters Podcast features a thought-provoking discussion on the transformative potential...