Hormonal Well-Being

06/27/2026

There's nothing like estrogen to prevent osteoporosis. Women gain more bone with estrogen (3.7%) than alendronate (1.4%) at 4 years. Women taking estrogen have fewer fractures (followed 11-35 years) without any risk of atypical fractures or jaw osteonecrosis.

There's simply nothing better!
https://buff.ly/BMaOdZm

06/24/2026

🧠 June is Alzheimer's & Brain Awareness Month.
Small daily amounts of lithium orotate (0.5 - 5 mg a day) may keep brain cells healthier as we age thus reducing the risk of Alzheimer's dementia.

See this review in JAMA Psychiatry.
https://buff.ly/4LKOPv4

This narrative review synthesizes more than 75 years of evidence to evaluate lithium’s evolution from mood stabilizer to candidate neuroprotective intervention.

06/21/2026

To the dads who give us wings!
Happy Father'd Day!

06/20/2026

Does your menopause treatment feel… generic?
With a protocol that doesn’t feel right?
That’s because many approaches are built for efficiency—not for you.

✨ With over 20 years of hormone experience each, we take the time to listen, understand, and customize your care.

Because feeling better shouldn’t be one-size-fits-all.

📞 713-714-7523
🌐 www.hormonalwellbeing.com

06/18/2026

June is Dementia Awareness Month. If you’re 50 or older and have been undecided about the shingles (herpes zoster) vaccine, a recent study (PMID 39733478) shows a lower risk of dementia in persons who received the vaccine by more than 30%.

06/15/2026

Does this photo cause you to panic?
Are you always looking for the bathroom? Do you fear certain exercises?

It's World Continence Week:
Over 60% of women deal with urinary incontinence. We at Hormonal Well-Being have many solutions: hormones, HIFEM, ThermiVa, PRP, Leva, PT ...
Let us help!
www.hormonalwellbeing.com
713-714-7523

06/13/2026

DON'T COUNT CALORIES, COUNT CHEMICALS!!
LIMIT PROCESSED FOODS!
New studies suggest certain food colorings and preservatives may increase risks for type 2 diabetes, cancer, and cardiovascular disease. Researchers recommend limiting exposure to these additives and prioritizing minimally processed foods for better health outcomes.
https://buff.ly/IBJs7JE

06/05/2026

Vitamin D May Help Protect the Brain 🧠☀️

A large study of more than 12,000 older adults found that people taking vitamin D supplements had a 40% lower risk of developing dementia compared with those who did not take vitamin D. The protective effect was especially strong in women, individuals with normal cognition at baseline, and those without the APOE ε4 genetic risk factor. Researchers concluded that vitamin D supplementation may be a promising strategy for dementia prevention. https://buff.ly/BBGR4wo

✨ While vitamin D isn't a cure for dementia, maintaining optimal vitamin D levels may be one more way to support long-term brain health as we age.

📞 Interested in optimizing your hormones, vitamins, and overall wellness? Contact us at 713-714-7523 or visit Hormonal Wellbeing to learn more.

06/04/2026

The growing body of vitamin D research continues to be compelling. Several studies have found that maintaining vitamin D levels in the upper quartile (>75 nmol/L) is associated with reduced colorectal cancer risk, reduced breast cancer risk, and lower cancer mortality. PMID: 27993551, 24596354, 30796437, 37004841.

06/03/2026

HAPPY FATHER'S DAY!

& Summer is upon us!

NOTE THE FOLLOWING DAYS MAY HAVE LIMITED CLINIC HOURS, BUT PHONE LINES SHOULD BE OPEN: JUNE 8,18,19.

Sorry in advance for any inconvenience.

Peptides: Promise, Hype, and What We Actually Know (continued)

There’s growing excitement around peptides and their potential to support healing, aging, and performance. In the future, we may be able to tailor precise peptide combinations to individual needs. For now, this space is somewhat of a “Wild West”—full of promising claims, but also limited regulation, incomplete research, and many unknowns.

In the May Newsletter, I discussed GHK-cu, BP157, and TB500.

In this newsletter, I will focus on Growth Hormone Releasing Hormone (GHRH, like sermorelin, ipamorelin, and tesamorelin), PT141, and KPV.

Possibly in the future… MOTS-c, Epithalon, Semax, Selank

1. Growth Hormone–Releasing Hormone (GHRH)

(Examples: sermorelin, tesamorelin, ipamorelin)

These peptides work by signaling the body to produce more of its own growth hormone naturally. Sermorelin and tesamorelin are the most researched options and have been FDA-approved for certain medical uses. While initially used to help treat conditions involving muscle loss, they are increasingly utilized in wellness medicine to support healthy aging, body composition, recovery, and overall vitality.

What they may do:
• Increase muscle mass and bone density
• Reduce visceral fat
• Improve body composition
• May have favorable effects on cholesterol
• May improve sleep

Common usage patterns: Cycled dosing (e.g., 5 days on, 2 days off, AND 3 weeks on/1 week off) to reduce tolerance and ineffectiveness.

Risks & considerations:
• Can increase blood glucose levels and insulin resistance
• May potentially stimulate cancer growth, as growth hormone pathways can influence cell proliferation
• Long-term safety data remains limited outside of specific medical indications
• Joint and nerve pain
• Fluid retention (edema)

--NOT RECOMMENDED FOR PERSONS WITH DIABETES OR CANCER--
____

2. PT-141
PT-141 (Bremelanotide) is a synthetic peptide that acts as a non-selective melanocortin receptor agonist. It is FDA-approved under the brand name Vyleesi for treating Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women and has also been heavily researched as an "on-demand" treatment for erectile dysfunction (ED) in men. It is difficult to get insurance to cover the medicine, but is easily compounded.

Key Benefits
• Boosts Sexual Desire: Stimulates neurons in the hypothalamus to increase libido and arousal.
• Treats Erectile Dysfunction (ED): Facilitates pe**le erections by acting centrally on the nervous system rather than relying strictly on peripheral blood flow.
• Research indicates it is a viable alternative for men who do not respond well to medications like sildenafil (Vi**ra).
• Rapid Onset: It typically takes effect within 45 to 60 minutes after subcutaneous injection, with effects lasting anywhere from 4 to 12 hours.

Known Risks and Side Effects (generally well tolerated)
• Nausea: The most frequently reported side effect.
• Cardiovascular Effects: Can cause a transient increase in blood pressure (approx. 2-6 mmHg) and a temporary decrease in heart rate.
• Hyperpigmentation: Darkening of the skin, gums, or existing moles can occur, particularly with frequent use (e.g., more than 8 doses per month).
• Facial flushing and headaches--usually mild.
____

3. KPV
KPV (Lys-Pro-Val) is a potent, naturally occurring tripeptide regarded for its targeted anti-inflammatory properties, capacity to stabilize mast cells, and ability to inhibit histamine release, all without broadly suppressing the immune system.

Key Benefits
• Histamine Reduction: KPV stabilizes mast cells and prevents mast cell degranulation, potentially offering marked relief from histamine intolerance, Mast Cell Activation Syndrome (MCAS), flushing, and allergic reactions.
• Systemic Inflammation: Research demonstrates its efficacy in calming inflammatory bowel disease (IBD) and respiratory inflammation.
• Gut Health: KPV promotes the repair of the intestinal epithelial barrier, aiding in the recovery of "leaky gut" and post-antibiotic dysbiosis.
• Skin and Tissue Healing: It accelerates wound healing, minimizes scar tissue, and soothes inflammatory skin conditions like eczema, psoriasis, and dermatitis

Primary Risks & Limitations
• Not FDA Approved: Because of the lack of human clinical trials. It is not approved by the FDA for any specific medical condition.
• Side Effects: When administered via subcutaneous injection, KPV can occasionally cause localized injection site reactions or mild, temporary flu-like symptoms.
____

Bottom Line
Peptides represent an exciting and evolving area of medicine with real potential—especially in healing, recovery, and aging-related therapies.

However:
• Many uses are not yet well studied in humans
• Products are often unregulated
• Long-term safety is still unclear
• Some mechanisms (like increased blood vessel growth) may carry theoretical risks, including tumor progression

In short: promising tools, but not without caution.

If you’re considering peptides, it’s important to have a thoughtful, individualized discussion about potential benefits, risks, and safer, evidence-based alternatives.
____

References:
GHRH:
PMID 28400207, 25555516, 18046908
PT-141:
PMID 31893927, 12851303, 18206919, 35147466
KPV:
PMID: 22837805, 18061177
revolutionhealth.org/blogs/news/peptide-therapy-kpv

Lastly, we continue to have days where our HIFEM treatments are half off, and other treatment specials. Although not included here, ask us about hair restoration and laser hair removal!

If interested, please arrange with Ruby.

HALF-OFF EMSHAPE
Build, tone, and strengthen with High-Intensity Focused Electromagnetic (HIFEM) technology—the equivalent of 20,000 crunches, squats, or Kegels in one session!
Perfect for abs, glutes, arms, or pelvic muscle strength (including bladder control).
30 minutes — $150 (reg. $300)
45 minutes — $225 (reg. $450)


VIPeel Specials — Buy 2, Get 1 FREE!
We LOVE VIPeels—and you will too!

VIPeel Advanced — for wrinkles, scarring, and loss of elasticity
Regularly 3 for $700 → Now 3 for $550!

VIPeel Precision Plus — for dark spots, melasma, and sun damage
Regularly 3 for $800 → Now 3 for $600!

VIPeel Body — reduces pigmentation, stretch marks, and scars
Regularly 3 for $800 → Now 3 for $600!

VIPeel Purify Precision with Peptides — everything Precision Plus does plus acne treatment benefits
Regularly 3 for $880 → Now 3 for $700!

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