06/02/2026
We've had a lot of interest in the new Valeda light therapy for dry age-related macular degeneration (AMD). Here are a few frequently-asked questions that I have gotten:
1. Who is a candidate for Valeda treatment?
Valeda light therapy is approved for intermediate or advanced nonexudative (or "dry") AMD. In the studies, patients were enrolled if their best-corrected visual acuity was 20/32 or worse. Most patients that I see are considered 'mild' AMD and their vision is unaffected by the disease. There are specific criteria to classify someone as intermediate AMD, which I would estimate represents as much as 15-20% of our practice's patient population with AMD.
2. What are the benefits of Valeda light therapy?
The benefits are two-fold. First, a large portion of patients undergoing treatment GAIN vision back. More than 60% of the patients enrolled in the study improved their vision by one line on the eye chart or more. About one-out-of-four patients gained two lines of vision. This sort of thing has never been seen before in the world of AMD. No other treatment available (past or present) has ever been able to show IMPROVEMENT in vision.
Second, the treatments significantly reduced the risk of LOSING vision. Patients getting Valeda light therapy were 2-3 times less-likely to lose visual acuity over the study period. Further, there was a reduction of progression to geographic atrophy. Patients getting Valeda light therapy were 10 times less likely to develop this blinding form of dry AMD at 1 year from the start of treatment.
3. Is this for real?
Yes, this is real. I get it -- light therapy...really? Skepticism about new technology is good and natural, but the data is compelling. More importantly, nothing else out there in the history of our treatment of AMD has ever done anything other than attempt to slow the inevitable blindness that ensues from the progression of the disease. There have been historically no other options besides taking AREDS vitamins, quitting smoking, and hoping for the best. Those treatments have existed for decades, and we unfortunately still see patients going blind from AMD regularly.
Novel treatments always take time to gain popularity. For example, the first intraocular lens with cataract surgery was implanted in 1949 by Sir Harold Ridley. It wasn't until the 1970's that intraocular lenses became an accepted practice. In the meantime, Dr. Ridley persevered ridicule by the ophthalmology community at large. He was later knighted by the Queen of England in 2000 for his achievements (over 50 year later). Now, effectively every cataract surgery performed is done with an intraocular lens implantation at the same time. Resistance and skepticism for new technology is potentially a good thing (the increasing use of AI, for instance), but I think that giving my patients choices is also a good.
4. What does treatment with Valeda entail?
Treatment involves staring at a specific sequence of light wavelengths for a 5-minute period per eye. One series of treatments requires 9 treatments over a 5-week period. Four series of treatments are recommended per year. The protocol is rigorous, but fortunately each individual treatment is quick, and the visit will be designed to be very efficient.
5. Where will you be offering this therapy?
Our Valeda unit is located at our Amherst office at 2875 Niagara Falls Boulevard. If there is sufficient demand, we are considering placing a unit at our Orchard Park location as well in time.
For those who have made it this far in the post, thank you for your attention.
***Figure attached produced from LIGHTSITE III Trial data (Boyer et. al 2024).