The ADA Forsyth Institute

The ADA Forsyth Institute Established in 1910, ADA Forsyth is a world leader in oral health research, education, & outreach. Based in Somerville, MA.

Founded in 1910 as a dental infirmary for disadvantaged children, the Forsyth Institute has a proud history of not just meeting the oral health needs of kids – but exceeding the traditional limits of oral medicine. In the mid-1900s, researchers at Boston-based Forsyth revolutionized the oral health profession when they discovered the connections between dental decay and bacteria. Building on these

revelations, the Institute has become an independent research organization dedicated to advancing human health and well being through scientific discovery and education. Although our hallmark is the study of oral health, our focus has widened over time to include the investigation of such diverse areas as diabetes, cardiovascular disease, and regenerative medicine. We have adopted this multidisciplinary research approach in order to analyze and prevent the severe systemic ramifications of oral infections. The world's most trusted authority in our field, we have a reputation for redefining convention – and we've made a century-long commitment to the community. Our work has inspired our profession to re-examine the scientific basis for oral disease. Today, the gifted scholars from around the globe who join our quest are dedicated to achieving a new generation of breakthroughs in oral health and disease prevention. Forsyth, an independent non-profit organization, is affiliated with Harvard School of Dental Medicine and Harvard Medical School and has collaborations with university and research organizations around the world.

🎉 ADA Forsyth’s Annual Fundraising Event is just 1 month away! 🎉2026 has already been an outstanding year for ADA Forsyt...
05/29/2026

🎉 ADA Forsyth’s Annual Fundraising Event is just 1 month away! 🎉

2026 has already been an outstanding year for ADA Forsyth – and the year is only half over!

Join us at Renaissance Golf Club on June 29 to celebrate our wins and sustain the future of oral health.

Connect with the all-star researchers, advocates, and clinicians who power our legendary and award-winning research and community programs.

Network with leaders from ADA Forsyth, the American Dental Association, and the oral health and life sciences community.

We’ll have plenty of delicious food, leisure time in the sun, and networking activities for all participants – whether you’re on or off the course!

All tickets and sponsorships for this event are tax-deductible and will directly aid our mission-driven activities in cutting-edge basic research, creative translational science, innovative clinical techniques, education, and public health outreach.

Register today! https://ow.ly/6QVn50Z5Hlx

Congratulations to all of the companies selected to present their innovations at the inaugural dentech-Asia conference o...
05/28/2026

Congratulations to all of the companies selected to present their innovations at the inaugural dentech-Asia conference on May 11-12 at the Seoul National University Siheung Campus Convention Center.

Two winners were selected for their innovative dental solutions:

NIBEC – Winner, Technology Showcase, Post-Revenue Companies

IR Scientific – Winner, Pitch Competition: Pre-Revenue Companies

Congratulations, NIBEC and IR Scientific!

Read more about dentech-Asia 2026 @ Seoul: https://ow.ly/g87a50Z5gEe

👀 and…watch this space for announcements about presentation opportunities at dentech in Boston this September!

Big news for ADA Forsyth! For the first time since 2010, ADA Forsyth is the No. 1 U.S. dental institution in the NIDCR r...
05/22/2026

Big news for ADA Forsyth! For the first time since 2010, ADA Forsyth is the No. 1 U.S. dental institution in the NIDCR rankings for FY2025.

ADA Forsyth researchers continue a 116-year legacy of high-quality science, earning competitive funding to advance dental and craniofacial research through sustained commitment to rigorous, innovative research. ADA Forsyth has ranked in the top 10 in NIDCR funding for each of the 24 years since NIDCR began releasing its rankings.

Congratulations to the entire ADA Forsyth team on this milestone, and a sincere thank-you to everyone who makes our work possible with your support and partnership!

Interested in joining team AFI? We’re recruiting top scientists to join our all-star faculty in our key areas of Microbiology, Inflammation and Immunology, and Craniofacial Biology and Bioengineering.

Get the full story here: https://forsyth.sharepoint.com/:f:/s/AFIPublic/IgDgRNfcLyE7QKFTcA0ANdMwASVwKnS-LgItmAtcdqzirs8?e=ZDc50V

American Dental Association

That’s a wrap on the very first ADA Forsyth dentech-Asia! Thank you to everyone who joined us in South Korea on May 11–1...
05/18/2026

That’s a wrap on the very first ADA Forsyth dentech-Asia! Thank you to everyone who joined us in South Korea on May 11–12.

Dentech-Asia brought together key opinion leaders, investors, researchers, and innovators from across the globe for two days of high-impact conversations to shape the future of oral health.

A sincere thank-you to our Gold Sponsor, ODS, and to all of our generous sponsors who made this event possible: Perkins Coie LLP, IR Scientific, Angel Aligner, Revere Partners, Tuuthfairy, Innobio, and Derbarzt.

Stay tuned for more dentech-Asia photos, recaps, and exciting announcements!

🦷🪥 Do you have red or bleeding gums? You may be eligible for a paid research study. The Center for Clinical & Translati...
05/15/2026

🦷🪥 Do you have red or bleeding gums? You may be eligible for a paid research study.

The Center for Clinical & Translational Research (CCTR) is currently seeking volunteers for a 6-week, 3-visit study to test a new (investigational) mouthwash in reducing bacteria that cause gingivitis.

Eligibility: Massachusetts residents aged 18-65 years with Gingivitis (red and bleeding gums).

At a screening visit, providers will:

🦷 Review your medical and dental history

🦷 Examine your teeth, gums, and mouth

🦷 Determine if you are eligible for the study

Please note: Participants must reside in MA and must be able to travel independently to the Center for Clinical and Translational Research, located at the ADA Forsyth Faculty Associates Dental Clinic at 100 Chestnut Street, Somerville, MA 02143 for the screening visit and all subsequent study visits. Compensation (up to $500) and parking will be provided.

👉 Sign up and schedule your screening visit today: https://forsyth.org/mouth-rinse-study/

Questions? Contact Molly Dunne at 617-892-8213, or email [email protected].

New research from ADA Forsyth sheds light on one of oral microbiology's biggest mysteries. Lead author Dr. Deepak Chouha...
05/12/2026

New research from ADA Forsyth sheds light on one of oral microbiology's biggest mysteries. Lead author Dr. Deepak Chouhan, Associate Professor Dr. Batbileg Bor, and a team of collaborators published a new study in Nature Communications revealing previously unknown details about how ultrasmall Saccharibacteria, from human "microbial dark matter," interact with human gingival epithelial cells.

The team found that Saccharibacteria cluster TLR2 receptors and are internalized via caveolin-mediated endocytosis, effectively dampening the inflammatory response triggered by other bacteria. It's a major mechanistic breakthrough with implications for understanding and potentially treating periodontitis.

Learn more at the link in this post: https://forsyth.org/ada-forsyth-study-breaks-new-ground-on-how-oral-microbial-dark-matter-modulate-human-innate-immune-responses/

Debuting in Seoul on May 11-12, dentech-Asia will convene key opinion leaders in oral health from around the globe. This...
05/04/2026

Debuting in Seoul on May 11-12, dentech-Asia will convene key opinion leaders in oral health from around the globe. This landmark event will build a bridge between investment and innovation, opening doors to East-West collaboration and accelerating oral health technology like never before.

Following thoughtful panel discussions and startup pitch sessions, participants will engage in exclusive networking opportunities to forge new partnerships.

Our program is packed with groundbreaking sessions, such as:

- How Academic Titans Turn Ideas into Impact

- Navigating the US Dental Innovation Ecosystem

- Q&A Session with ADA Forsyth

- An Inside View: How Investors Make Decisions

- A Look Inside the SNU-AFI Joint Research Center

- Remarks on Oral Health Innovation Across the Globe

- 2 Technology Showcase sessions

- And more...

A huge thank you to our Gold Sponsor, ODS Resin, and all of our event sponsors for their generous support.

Join us May 11–12 in Seoul. Registration is still open for a limited time. Learn more about the program and register here: https://forsyth.org/events-courses/dentech-asia-2026/

04/29/2026

How do we verify the levels of active ingredients released from toothpaste in the first minute of brushing?

Professional scientists at ADA Forsyth’s ADA Seal of Acceptance testing program run a controlled one-minute release test to measure fluoride availability under simulated brushing conditions.

Testing begins with precise preparation, accurately weighing toothpaste and working solution into syringes. The sample is then transferred back and forth between syringes for one minute, replicating the mechanical action of brushing.

From there, the sample is processed through a series of analytical steps: centrifugation, filtration, and controlled dilution to prepare for instrumental analysis.

Ion chromatography quantifies fluoride concentration with high precision. This data is cross-checked against alternative analytical methods to ensure consistency and reliability.

The goal is simple but critical: manufacturer-stated fluoride levels must align with levels of fluoride measured in testing.

This work supports the ADA Seal of Acceptance program, trusted by clinicians and consumers to ensure that products meet the highest standards.

We are extremely proud to share that ADA Forsyth Institute officially accepted our Gold Award (Greater Boston Region) at...
04/17/2026

We are extremely proud to share that ADA Forsyth Institute officially accepted our Gold Award (Greater Boston Region) at MassEcon's Team Massachusetts Economic Impact Awards Gala last evening 🏆

This award recognizes the economic impact of our move to 100 Chestnut St., City of Somerville which brings $100M+ in research funding, a growing workforce, and expanded research and clinical capacity to our new community.

Representing AFI at the awards ceremony were team members across the administration, clinical care and research units, as well as new and longtime friends and supporters including JLL Managing Director Robert Coughlin, a City of Somerville representative, Board members Dr. Maria Ryan, Dr. Jonathan Knapp, and Dr. Nader Nadershahi.

In his acceptance speech, CEO Dr. Wenyuan Shi reflected on 116 years of foundational discoveries, from establishing one of the first dental hygiene schools in the nation to pioneering fluoride research.

Thank you, MassEcon! We look forward to continuing to support innovation and development across the Commonwealth! 🦷

What a year at IADR! We finished the conference with a fantastic reception attended by many members of the ADA Forsyth a...
04/02/2026

What a year at IADR! We finished the conference with a fantastic reception attended by many members of the ADA Forsyth alumni community. We're so grateful to everyone who joined us there, stopped by our booth, or attended our scientists' presentations. Your support means everything. See you in 2027!

Address

245 1st Street
Cambridge, MA
02142

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 6pm
Thursday 9am - 6pm
Friday 9am - 5pm

Website

https://www.forsyth.org/

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