Lighthouse Instruments

Call Directions Website Contact the practice

Lighthouse Instruments Solutions for Container Closure Integrity testing, Oxygen monitoring, Moisture determination and Media fill inspection.

LIGHTHOUSE offers complete solutions for headspace Oxygen Monitoring, Container Closure Integrity Testing, Moisture Determination and Microbial Contamination inspection of media vials. Our solutions include feasibility studies, process and packaging studies, method development, method validation protocols, automated or benchtop lease platforms, on-site trouble shooting and support. Rapid, nondestructive, laser-based headspace analysis is suitable for applications specific to the sterile pharmaceutical industry. It is a useful analytical tool to generate statistical process and product data in all stages of the product life cycle, from Development to Manufacturing and Quality Control. LIGHTHOUSE Instruments is the leading provider and manufacturer of headspace analysis platforms and measurement services. Contact us for a free demo, feasibility study, or other information.

10/05/2026

Regulations for sterile drug products in Asia Pacific are moving steadily closer to European and US standards. For manufacturers who export, or plan to, this changes what you need to monitor and how you demonstrate compliance.

Meet Josephine Bouwman, Area Sales Manager for Asia Pacific, as she explains how we support manufacturers in the region with headspace oxygen monitoring and container closure integrity testing:
▪️ Process monitoring from packaging development through final product inspection
▪️ Guidance on meeting FDA and European requirements for export markets
▪️ Flexible support options, from full-service projects to leased or purchased instruments
▪️ Expertise built in our own lab, which is the heaviest user of our instruments

The goal is a long-term partnership, not just a one-off equipment sale. Behind that is something everyone in this industry shares: high-quality medicine, available to more people across the region.

Working on CCIT or headspace oxygen monitoring in the Asia Pacific? Send Josephine a message.

CPHI Milan is just around the corner, and we look forward to seeing you there.Visit us at Booth 9K99 to meet Dr. Marnix ...
10/01/2026

CPHI Milan is just around the corner, and we look forward to seeing you there.

Visit us at Booth 9K99 to meet Dr. Marnix Wieffer and Dr. Giovanni Auricchio, PhD, MBA.

They'll be on hand to talk about how our headspace analysis equipment and analytical services help you ensure container closure integrity and protect product quality.

Want guaranteed time with them?
Schedule a meeting:

Dr. Marnix https://go.oncehub.com/CPHIMilan_Marnix
Dr. Giovanni https://go.oncehub.com/CPHIMilan_Giovanni

See you in Milan!

09/25/2026

How well are your oxygen-sensitive formulations protected in staked needle syringes?

In this animation we evaluate oxygen permeation in staked needle syringes to see how well sensitive formulations are protected over time.

We measured headspace oxygen levels at the start of the study, then placed the syringes in different storage positions. Over a three-year monitoring period, headspace oxygen increased by 3.5% per year across all syringes, regardless of storage position.

▶️ Watch the animation to see what we did.

Join us in Melbourne this October!We're proud to be exhibiting at the PDA - Parenteral Drug Association Aseptic Manufact...
09/24/2026

Join us in Melbourne this October!

We're proud to be exhibiting at the PDA - Parenteral Drug Association Aseptic Manufacturing Excellence Conference, October 14 to 15 in Melbourne, Australia.

Find us at booth #3 to talk with our expert Clive Seymour to learn more about headspace analysis for automated media fill inspection.

We look forward to connecting with you.

New Product Note Available | LIGHTHOUSE CCI TesterContainer closure integrity (CCI) is critical for ensuring the sterili...
09/17/2026

New Product Note Available | LIGHTHOUSE CCI Tester

Container closure integrity (CCI) is critical for ensuring the sterility and stability of pharmaceutical products. As the industry shifts toward deterministic and non-destructive methods, reliable and reproducible CCIT solutions are becoming essential.

The LIGHTHOUSE CCI Tester is designed to support packaging development, routine QC, and even batch release testing — all on a single analytical platform.

The LIGHTHOUSE CCI Tester provides:
▪️ Automated and reproducible conditioning cycles
▪️Non-destructive and deterministic CCIT with laser-based headspace analysis
▪️Detection of defects from 0.1 micron to gross defects
▪️21 CFR Part 11 compliant data management
▪️Support for vials, syringes, cartridges, autoinjectors, and more

Because laser-based headspace analysis is a true platform technology, the same validated method can be used throughout the entire product lifecycle — from early package development to commercial manufacturing.

This creates a consistent and scalable approach to CCIT while reducing method variability and simplifying implementation across development and production environments.

Read the new Product Note to discover how to strengthen your container closure integrity strategy. Read here https://lighthouseinstruments.com/knowledge-center/cci-tester/

At LIGHTHOUSE, we use laser-based headspace analysis to directly test fully assembled combination products in accordance...
08/28/2026

At LIGHTHOUSE, we use laser-based headspace analysis to directly test fully assembled combination products in accordance with USP principles.

The result?
Reliable, non-destructive integrity testing that helps streamline qualification activities, and supports a life-cycle approach to CCI.

Want to discuss testing for your autoinjectors or explore how our expert team can streamline the qualification of your autoinjectors?

📩 Send us a direct message today!

🔬 Missed our live webinar on Direct CCI Testing of Fully Assembled Autoinjectors? It's now available on-demand.As regul...
08/19/2026

🔬 Missed our live webinar on Direct CCI Testing of Fully Assembled Autoinjectors? It's now available on-demand.

As regulatory expectations continue to evolve, manufacturers face increasing pressure to adopt validated, deterministic methods that comply with standards such as USP , USP , and EU Annex 1.

Presented by Dr. Francesca Caprioli, this session explores how laser-based headspace analysis enables direct testing of fully assembled autoinjectors without device disassembly.

💡 What you'll learn:
▪️ How to align your CCI strategy with current and emerging regulatory expectations
▪️ How one technology can support CCI testing throughout the entire product life cycle, from development to stability studies
▪️ How to eliminate device disassembly and reduce the risk of product damage, variability, and compromised results

Discover how headspace analysis is helping pharmaceutical manufacturers modernize CCI testing while improving efficiency, compliance, and product integrity.

🎥 Watch the full session on-demand, free.

👉 https://lighthouseinstruments.com/knowledge-center/ensure-container-integrity-without-compromising-your-autoinjectors/

Another great CCIT Workshop in partnership with Genesis Packaging Technologies, this time in Blue Bell, Pennsylvania!We ...
08/17/2026

Another great CCIT Workshop in partnership with Genesis Packaging Technologies, this time in Blue Bell, Pennsylvania!

We dove into Container Closure Integrity Testing (CCIT), took a holistic look at CCI strategy, walked through USP and USP compliance, and covered seal quality optimization with Residual Seal Force measurements.

Thanks to everyone who came out and made it such a strong session, great questions and great energy.

Couldn't make it to Pennsylvania? We're bringing the workshop to 📍 Lexington, Massachusetts, at Scottish Rite Masonic Museum.
📅 October, 15 - 2026

Speakers joining us: Dr. Jim Veale, Tom Millner, Jay Rowden, Dr. Carolina González Gaitán and Kevin Stofflet.

🚨 It's free to attend, but space is limited and filling up fast!
➡️ Full agenda herehttps://lighthouseinstruments.com/wp-content/uploads/2026/08/Lighthouse-Genesis-Workshop-flyer_Lexington-MA_v1.pdf

Regulatory expectations for container closure integrity testing keep tightening — and many labs still rely on methods th...
08/14/2026

Regulatory expectations for container closure integrity testing keep tightening — and many labs still rely on methods that can't keep pace across the full product lifecycle.

At CPHI Milan (October 6–8, 2026), see how our new CCI Tester addresses this: a deterministic, non-destructive platform built for CCIT from early development through commercial production.

Find us at Hall 9, 📍 Booth 9K99. Dr. Steven de Vries, Dr. Marnix Wieffer and Dr. Giovanni Auricchio, PhD, MBA will walk you through validation data and discuss method development tailored to your product.

📅 Book a meeting in advance here - https://go.oncehub.com/CPHIMilan_Marnix

See you in Milan!

08/10/2026

CCI testing, water activity, oxygen monitoring, moisture mapping — supporting a product through its full life cycle can take more than one method.

LIGHTHOUSE Analytical Services covers laboratory testing, onsite testing, and recertification, backed by our GMP and R&D labs in Amsterdam and Charlottesville.

Watch the video to see what we can do for you.

Address

2050 Avon Court
Charlottesville, VA
VA22902

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

Telephone

+31207051050

Website

Alerts

Be the first to know and let us send you an email when Lighthouse Instruments posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Lighthouse Instruments:

Shortcuts

Share

Category