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Vitract We pair gut testing technology with precision nutrition to promote better mental health outcomes.

10/26/2026

Blood work alone was missing the picture.

Rejuvenating Health introduced gut health testing a year ago and has since made it mandatory for every new client. The reason: women presenting with hormonal symptoms were completing blood work, getting treated, and still not feeling better. The gut test was showing actionable findings that should have been addressed first.

The gut is upstream of thyroid function, estrogen metabolism, and a range of hormonal presentations. Bowel irregularity, whether too slow or too fast, is often the first clinical signal that something deeper is off.

Blood panels and gut tests are asking different questions. Running one without the other leaves gaps.

10/25/2026

Intestinal permeability markers drop measurably in seven to fourteen days with lifestyle changes alone.

Lactulose/mannitol ratios, zonulin, LPS binding protein, the numbers move without medication. Diet and lifestyle interventions produce measurable changes in gut integrity on a short timeline.

A patient can have an optimized supplement protocol and still not improve if the foundational inputs are working against it. Before adding, the question is what is already in place.

Understanding what a patient’s life actually looks like before handing them a protocol is a clinical skill.

10/24/2026

Estrogen has a documented protective role in cardiovascular, neurological, and bone health. Its impact on the gut is less discussed.

Estrogen supports gut integrity. When levels drop, gut function can decline alongside it, which creates downstream effects on thyroid conversion, inflammation, and overall hormone metabolism. Addressing the gut without considering estrogen status, or addressing estrogen without considering the gut, means working with only part of the picture.

The Women’s Health Initiative shaped a generation of clinical hesitancy around HRT. The research since then has complicated that picture significantly.

For women experiencing gut-related symptoms after menopause, a small amount of estrogen may support gut function enough to correct issues that would otherwise require additional medications to manage.

10/23/2026

HRT can make some women feel worse, and the microbiome is often why.

The estrobolome is the collection of gut microbial genes that governs how estrogen is metabolized and expelled. When the estrobolome is compromised, estrogen that should be cleared gets recirculated instead. The result is bloating, weight gain, and mood disruption, even in women who are supplementing correctly.

This applies to premenopausal women too. Whether estrogen is endogenous or supplemented, the gut determines its fate.

A woman who starts HRT and feels worse is worth looking at from a microbiome standpoint before adjusting her protocol.

10/22/2026

Gut testing can flag nutrient absorption issues before blood labs confirm them.

B12 and K2 depend heavily on microbial synthesis. A gut microbiome report shows predicted microbial production capacity for both, so low levels on the report often correlate with low serum levels before a blood draw catches it.

Low microbial B12 production presents clinically as fatigue, hair loss, and anxiety. Low K2 affects vitamin D absorption and bone metabolism.

Supplementing without addressing gut absorption is throwing money away.

10/21/2026

Low serotonin can be a microbial problem.

Ninety-five percent of serotonin is produced by enterochromaffin cells. But gut microbial metabolites activate those cells to produce it. Butyrate, a short-chain fatty acid, is one of the key activators.

When a patient presents with low serotonin, two things are often happening at once. Microbial contribution to serotonin is low, and butyrate is low, which means the enterochromaffin cells are receiving less activation signal. The total serotonin pool drops from both directions.

Look for that pattern alongside the serotonin number.

What’s next in nutritional therapy? 🔬Join us at The Precision Health Forum for an afternoon exploring the science, testi...
10/20/2026

What’s next in nutritional therapy? 🔬

Join us at The Precision Health Forum for an afternoon exploring the science, testing and tools shaping clinical practice. Hear from experts in mineral balance, peptides and bioregulators, and microbiome health, with insights you can bring back to your clients.

đź“…Friday, November 20, 2026
⏰2:00–6:30 PM
📍Wallacespace Spitalfields, London

Your ticket includes expert-led sessions, a panel discussion and audience Q&A, food and drinks, and time to connect with fellow practitioners.

🎟️Seating is limited, so secure your place today: https://theprecisionhealthforum.com/

10/20/2026

Elevated E. coli in a gut microbiome report can read as a stress marker.

E. coli can sense norepinephrine through a receptor called the QseC receptor, and that signal drives proliferation. Norepinephrine essentially functions as a substrate for E. coli growth. As those populations expand, some strains begin co-opting virulence genes, making them more disease-causing over time.

The feedback loop is the part worth paying attention to. E. coli also produces norepinephrine, so elevated E. coli responds to stress and amplifies it at the same time.

When a patient presents with high E. coli on their report, it is worth asking what else is going on systemically.

10/19/2026

Serotonin does not cause diarrhea or constipation on its own.

What it actually does is enhance smooth muscle contraction. It is the driver of peristalsis and colonic movement. And in a clinical context, what practitioners are more commonly seeing is that a lack of optimal colonic serotonin levels is what slows things down and contributes to constipation, not excess.

The gut produces the vast majority of the body’s serotonin. When that system is depleted, motility suffers. Most practitioners are not asking about serotonin when a patient presents with GI symptoms, even though they should be.

MEET THE SPEAKERS | THE PRECISION HEALTH FORUMThree experts. Three areas of health. One afternoon dedicated to advancing...
10/19/2026

MEET THE SPEAKERS | THE PRECISION HEALTH FORUM

Three experts. Three areas of health. One afternoon dedicated to advancing nutritional therapy and personalised care.

• Lisa Pitel-Killah: Mineral Balance in Clinical Practice: From Assessment to Better Outcomes
• Philip Micans, MS, PharmB: Bioregulators & Peptides: Emerging Tools for Health, Repair & Longevity
• Dr. Chidozie Ojobor, Ph.D.: Look Beneath the Symptoms: Using Microbiome Signatures to Uncover Root Drivers of Chronic Diseases

Join us for their sessions, followed by a panel discussion and audience Q&A.

đź“…Friday, November 20, 2026
⏰2:00–6:30 PM
📍Wallacespace Spitalfields, London

Seating is limited. Secure your place: https://theprecisionhealthforum.com/

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838 Walker Road
Dover, DE
19904

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Monday 9am - 7pm
Tuesday 9am - 6pm
Wednesday 9am - 6pm
Thursday 9am - 6pm
Friday 9am - 5:45pm

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