Polarean, Inc.

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Polarean, Inc.

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Comprehensive Imaging of Lung Function in One Breath We are committed to making this capability available in your lab and putting it under your control.

Polarean has acquired the key assets and intellectual property for commercializing hyperpolarized gas MRI technology. By enabling leading academic institutions and industry scientists to freely pursue innovative ideas and applications we seek to unlock the extraordinary promise of this novel technology. Whether it’s basic physics, chemistry, or clinical imaging, our mission is to encourage adoption and exploration of hyperpolarized gas technology.

10/08/2026

Headed to Philadelphia this month?

The Polarean team, including Alan Huang and Brady Anna, will be exhibiting at the Society for Pediatric Radiology’s 20th Symposium on Pediatric Cardiovascular MR Imaging, held at Children’s Hospital of Philadelphia from October 23–25.

Pediatric imaging often requires repeat exams over time, making patient comfort and minimizing radiation exposure just as important as the information the exam provides.

With a short breath hold, the XENOVIEW® MRI Platform provides a patient-friendly, noninvasive approach to quantify regional lung ventilation without ionizing radiation for patients aged 6 years and older.

Beyond its approved ventilation indication, research applications of Xenon MRI are expanding our understanding of cardiopulmonary physiology. Emerging measures of gas diffusion across the alveolar-capillary membrane and pulmonary microvascular hemodynamics are providing new ways to explore the connection between the lungs and cardiovascular system.

Stop by our table to learn how Xenon MRI can complement cardiovascular imaging 🫁🫀

For XENOVIEW® Important Safety Information and full Prescribing Information, please visit www.xenoview.net.

09/18/2026

Alex is heading to the International Workshop for Pulmonary Functional Imaging — a favorite week each year with the researchers and clinicians pushing functional lung imaging forward. Looking forward to the science and reconnecting with our IWPFI community. If you'll be there too, let's connect.

09/10/2026

ASTRO, here we come!

Daniel Booker and J. Fernando Corredor, Sales Directors at Polarean, will be attending ASTRO 2026 from September 26 through 30.

They look forward to connecting with colleagues and joining important conversations about functional lung avoidance and the evolving role of Xenon MRI in radiation treatment planning.

Will you be attending? Let us know if you would like to connect with Daniel ([email protected]) and Fernando ([email protected]) during the event. We look forward to seeing you at ASTRO!

08/28/2026

Xenon gas is basically invisible to a standard MRI.

So how does the XENOVIEW® MRI Platform turn a single 10-second breath into a full 3D map of lung ventilation?

Short answer: we boost that gas's signal by 10,000-fold — through hyperpolarization — before the patient ever inhales it.

Full Indication & Important Safety Information: link in bio.

08/21/2026

Why seeing mucus plugs matters in severe asthma 🫁

A recent review paper in Respiratory Research nicely elucidates that biologic therapy can reduce occlusive mucus plugs and improve functional outcomes, including ventilation defects measured by MRI.

Structural imaging with CT can identify the obstruction and Xenon MRI can determine the functional consequences of the mucus plug. It also can show where residual plugs remain after treatment. Xenon MRI offers noninvasive, radiation-free insight into regional lung function — supporting precise, personalized asthma care.

Read the full article: https://link.springer.com/article/10.1186/s12931-026-03501-z

Full Indication & Important Safety Information: link in bio.

08/19/2026

What makes Xenon MRI different?

Traditional imaging shows what the lungs look like. Xenon MRI shows how they actually work. 🫁

In an episode of The Healthcare Exchange, Pulmonogists Cedric "Jamie" Rutland MD FCCP and Chase Hall, MD discuss how functional imaging with Xenon MRI is changing the way physicians understand and treat lung disease.

Full Indication & Important Safety Information: https://polarean.com/

08/11/2026

We'll be in Denver at the AABIP Meeting in a few weeks, talking with the physicians who thread scopes and devices into lungs for a living. can assist in the regional functional map to guide the interventional procedure and visualize how it quantitatively restores the regional ventilation - all non-invasively, with no radiation exposure to child or adult.

If you are attending, let's talk. Connect with J. Fernando Corredor at AABIP, August 20–22.

07/22/2026

550,000,000+.
More than the entire U.S. population, multiplied by one and a half.

That's how many people worldwide are living with chronic lung disease today. 🫁

🫁 COPD: 380 million worldwide
🫁 Asthma: 260 million worldwide
🫁 Lung Cancer: ~2.5 million new cases diagnosed each year
🫁 Idiopathic Pulmonary Fibrosis: 3 million worldwide, median survival 3–5 years after diagnosis
🫁 Pulmonary Arterial Hypertension: ~1 in 100,000 people
🫁 Cystic Fibrosis: 100,000 worldwide
🫁 Long COVID respiratory complications: tens of millions and counting

Standard tests — spirometry, oxygen saturation, six-minute walks — are valuable. They don't show regional lung function.

The XENOVIEW® MRI Platform enables Xenon MRI: visualizing regional lung ventilation in a single breath hold, radiation-free. Available today as an FDA-approved, reimbursed exam. For ILD and PAH, we're researching the platform's potential in alveolar diffusion and micro-vascular hemodynamics — research-stage, not yet an approved use.

This is why we do this work.
Full Indication & Safety Info: link in bio.
🔗 Learn more: link in bio.

07/01/2026

Behind every bronchiectasis diagnosis is a person navigating the daily challenges of living with a chronic lung disease. Every breath matters, and timely, accurate diagnosis can help patients and their care teams make more informed decisions earlier in the care journey.

On World Bronchiectasis Day, we're reminded that continued innovation, research, and collaboration have the power to improve lives. At Polarean, we're committed to advancing functional pulmonary MRI technology that helps clinicians visualize the ventilation abnormalities that result from airway widening and damage that occurs complex respiratory diseases like bronchiectasis.

Together, we can help create a future where more patients receive the answers and care they deserve.

06/25/2026

What if Xenon MRI could help identify, with extremely high accuracy, whether a patient is healthy, has Interstitial Lung Disease (ILD), or has Chronic Obstructive Pulmonary Disease (COPD)?

A newly published study demonstrates how Xenon MRI moves beyond disease characterization and closer to clinical decision-making.

Using four key biomarkers derived from a Xenon MRI exam, researchers demonstrated the ability to distinguish ILD from COPD and from healthy participants with high sensitivity and specificity:

✔️ Areas of little or no airflow in the lungs (ventilation defect percentage)

✔️ Abnormal gas diffusion across the alveolar membrane (high membrane percentage)

✔️ Reduced capillary blood volume n the lower lungs (basilar red blood cell [RBC]defect)

✔️ Impaired blood oxygenation measured noninvasively (assessed through RBC xenon chemical shift)

Patients with chronic lung disease often undergo multiple tests before reaching a diagnosis, and differentiating between disease processes can be challenging. The ability to classify patients from a radiation-free functional imaging exam has the potential to support earlier diagnosis, improve diagnostic confidence, and guide patient management.

Read the study to learn more about research using Xenon MRI is shaping the future of lung health.

This study, with a novel decision tree algorithm, represents another important contribution from the team at Duke University Health System including, Fuyao Li, Dr. Suphachart Leewiwatwong, Dr. Hong Qin, Dr. Bryan O'Sullivan-Murphy, Dr. Aparna Swaminathan, Dr. David Mummy, and Dr. Bastiaan Driehuys, to the growing field of functional lung imaging.

Read more here: https://www.academicradiology.org/article/S1076-6332(26)00289-8/abstract

Address

2500 Meridian Pkwy Ste 175
Durham, NC
27713

Telephone

+19192067900

Website

http://www.polarean.com/

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