11/03/2026
Twenty years ago, my wife Carolyn was diagnosed with the bone density of a 90-year-old woman. Today, at 74, she's active, hiking and sailing, and her bone-density measurements have improved. Her progress wasn't one magic pill. It was a comprehensive commitment to nutrition, exercise and targeted nutritional support.
In Part Three of my osteoporosis series, I share the thinking behind Osteo-Max II, a new generation of nutritional bone support built around the biology of bone remodeling itself, not just calcium.
Your bones are living tissue, constantly remodeled. Osteoclasts remove old bone; osteoblasts build new bone. After menopause, declining estrogen, inflammation and metabolic changes can tip that balance. Instead of only slowing the demolition crew, why not support the construction crew?
Osteo-Max II features three botanicals at amounts matched to human clinical research:
OsteoCaf™ (600 mg daily): compounds from Dalbergia sissoo studied for activating BMP-2 and Wnt/beta-catenin signaling involved in bone formation, in a one-year human study of postmenopausal women.
Genistein aglycone (56 mg daily, closely matching the 54 mg used in clinical trials): in a two-year randomized controlled trial, women receiving genistein experienced improvements in bone mineral density while the placebo group declined. Its preferential ER-beta activity and favorable breast and endometrial safety profile in follow-up research make it especially interesting.
Icariin (60 mg daily from standardized Epimedium extract): in a 24-month randomized controlled trial, women receiving Epimedium-derived flavonoids maintained bone density at the lumbar spine and femoral neck while the placebo group lost bone.
Plus vitamin D3 (1,500 IU), vitamin K2 as MK-7 (200 mcg), zinc (16 mg), copper (1 mg) and boron (4 mg) for the nutritional tools of bone maintenance. No added calcium, so calcium intake can be individualized. Bio-Cal Citrate complements it when needed. And no strontium, avoiding the DEXA interpretation problem.
How do you know if your bones are responding? P1NP reflects bone formation and CTX reflects bone breakdown. Read alongside DEXA and a clinician's assessment, they offer another window into living bone. Waiting two years between scans to learn if a therapy is working is simply too long.
Learn more, read Dr. Fors' article here. Find the link in the first comment.
Biospec Nutritionals products are not intended to diagnose, treat, cure, or prevent any disease. This information is for educational purposes only and is not medical advice. Always consult your healthcare professional before starting any supplement program. Women with osteoporosis should continue appropriate medical assessment and management.