Pharmacy Exam

11/02/2026

FDA declared the semaglutide shortage over. When did 503B outsourcing facilities have to stop making copies?

A) February 21, 2025
B) April 22, 2025
C) May 22, 2025
D) March 19, 2025

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✅ Answer: C
FDA declared the shortage resolved on February 21, 2025. State-licensed 503A pharmacies got a short grace period that ended in April. 503B outsourcing facilities had until May 22, 2025. This is a pharmacy law topic, not medical advice.

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10/30/2026

USP 795 Beyond-Use Dates: PTCE Question of the Day

An oral suspension is water-based and contains a preservative. What is its default BUD under USP ?

A) 14 days
B) 90 days
C) 180 days
D) 35 days

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✅ Answer: D
Preserved water-based preparations get 35 days. Without a preservative, the limit is 14 days in the fridge. Nonaqueous oral liquids get 90 days. Other nonaqueous forms, like capsules, get 180 days.

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10/29/2026

Lenacapavir PrEP Dosing: NAPLEX Question of the Day

A patient starts lenacapavir for HIV PrEP. After the day 1 and 2 doses, how often is the injection given?

A) Every month
B) Every 2 months
C) Every 6 months
D) Once a year

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✅ Answer: C
Lenacapavir starts with an injection plus tablets on day 1 and tablets on day 2. After that, one injection every 6 months. The patient must test HIV-negative before each shot. Every 2 months is the dosing for cabotegravir PrEP.

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10/28/2026

Hormone Therapy Boxed Warning Update: FPGEE Question of the Day

FDA moved in 2025 to remove most boxed warnings from menopausal hormone therapy. Which one stays?

A) Probable dementia, all estrogens
B) Endometrial cancer, estrogen-alone
C) Breast cancer, estrogen + progestin
D) Stroke, vaginal estrogen

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✅ Answer: B
In November 2025, FDA moved to drop the boxed warnings for heart disease, breast cancer and dementia. The endometrial cancer boxed warning stays for systemic estrogen-alone products. That is why women with a uterus also need a progestin. Heart and breast cancer risks still appear as regular warnings.

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10/27/2026

DSCSA Small Pharmacy Deadline: MPJE Question of the Day

A pharmacy company has 18 full-time pharmacists and techs. When must it meet DSCSA enhanced electronic tracing?

A) November 27, 2025
B) November 27, 2023
C) November 27, 2026
D) November 27, 2027

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✅ Answer: D
A small dispenser has 25 or fewer full-time pharmacists and techs. In August 2026, FDA extended its exemption to November 27, 2027. The count is company-wide, not per store. Larger pharmacies had to comply by November 27, 2025. Other DSCSA duties still apply today.

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10/26/2026

First Drug for Sleep Apnea: NAPLEX Question of the Day

Which drug is the first one FDA-approved to treat moderate to severe sleep apnea in adults with obesity?

A) Modafinil
B) Tirzepatide
C) Semaglutide
D) Solriamfetol

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✅ Answer: B
FDA approved tirzepatide for moderate to severe obstructive sleep apnea with obesity in December 2024. It was the first drug for this use. It cut breathing events by about 25 to 29 per hour vs placebo. Modafinil and solriamfetol only treat daytime sleepiness. They do not fix the blocked airway.

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10/23/2026

10/22/2026

Buprenorphine Telemedicine Rule: MPJE Question of the Day

Under the DEA buprenorphine telemedicine rule (effective Dec 31, 2025), what must the pharmacist do before dispensing?

A) Confirm the prescriber’s X-waiver
B) Limit the fill to a 7-day supply
C) Require an in-person visit first
D) Verify the patient’s identity

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✅ Answer: D
The pharmacist must verify the patient’s identity before dispensing. A government ID works. So do other documents like a paycheck or utility bill. Prescribers can give up to 6 months total by telemedicine without an in-person visit. X-waivers ended in 2023. The 7-day limit only applies when the prescriber cannot check the PDMP.

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10/21/2026

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10/20/2026

Clozapine REMS Update: PTCE Question of the Day

As of 2025, which drug no longer needs a REMS check before the pharmacy can dispense it?

A) Isotretinoin (iPLEDGE)
B) Clozapine
C) Lenalidomide
D) Sodium oxybate

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✅ Answer: B
FDA removed the clozapine REMS on June 13, 2025. Pharmacies no longer need REMS enrollment. They no longer check ANC results before dispensing. ANC monitoring is still recommended in the label. iPLEDGE, the lenalidomide REMS and the sodium oxybate REMS are all still active.

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