Simply You

10/24/2026

🛩It's been about 7 yrs since Harley traveled by plane, so he doesn't remember much. The two of us are sneaking away for the weekend to visit his big bro at UC Berkeley. It's only been 2 months since we saw Daniel, but that's 2 months too long to go without hugs & our weekend midnight philosophical chats! Harley was nervous at take off but by the time we landed, he said it was fun!

09/18/2026

On Monday this cute munchkin turned 11! He is sweet, loving, empathetic, wild, stubborn, & the most gentle soul. We are so proud of the person he is growing into 💕

09/11/2026

09/11/2026

That's where C*D fits in! C*D interacts with the ECS & other signaling systems involved in how our bodies respond to stress - which is why I consider it a tool for stress support!

09/08/2026

🌱 The endocannabinoid system (ECS) is a signaling system found throughout the body that helps regulate multiple physiologic processes & contributes to homeostasis—your body's ongoing effort to maintain internal balance.
🌿Your body produces its own signaling molecules called endocannabinoids, including anandamide (AEA) & 2-AG. These interact with cannabinoid receptors—including CB1 & CB2—& are then synthesized or broken down by enzymes as needed.
👉So why are we talking about this during our series on stress? Because the ECS interacts directly with the body's stress-response circuitry. Research suggests endocannabinoid signaling participates in both the activation & recovery phases of the HPA-axis response to stress. In other words, this isn't simply a “C*D system.” It's one of the body's own regulatory systems.
🌿And that's where our conversation about C*D actually begins. Not with cannabis. With human physiology. 🧠🌱
💚 Simply You Integrative Health | Restore • Nourish • Heal

1. Morena M, Patel S, Bains JS, Hill MN. Neurobiological Interactions Between Stress and the Endocannabinoid System. Neuropsychopharmacology. 2016 Jan;41(1):80-102. doi: 10.1038/npp.2015.166. Epub 2015 Jun 12. PMID: 26068727; PMCID: PMC4677118.
2. Hill MN, Patel S, Campolongo P, Tasker JG, Wotjak CT, Bains JS. Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output. J Neurosci. 2010 Nov 10;30(45):14980-6. doi: 10.1523/JNEUROSCI.4283-10.2010. PMID: 21068301; PMCID: PMC3073528.

09/07/2026

Your nervous system doesn't care that the tiger is actually an email. 🐅📧

09/04/2026

We're talking stress physiology all month!

09/02/2026

😟Think stress is “just in your head”? Your adrenal glands would disagree😟
😵Stress is a normal survival response. When your brain perceives a threat—whether that's an actual emergency or today's nonstop deadlines, finances, traffic, family demands, notifications, & lack of downtime—it activates your sympathetic nervous system & HPA axis (hypothalamic-pituitary-adrenal axis). Your adrenal glands release hormones including adrenaline & cortisol to increase available energy & keep you alert & ready to respond. In short bursts, that is exactly what your body is designed to do!

😩The problem is when the stressor ends…but your body rarely gets the message. Chronic stress can disrupt normal HPA-axis & cortisol regulation & increase allostatic load—the cumulative physiologic burden of repeatedly adapting to stress. And because your stress response interacts with your nervous, cardiovascular, immune, metabolic, gastrointestinal & musculoskeletal systems, stress can show up in ways that do not necessarily feel psychological.

😬Poor sleep. Digestive changes. Headaches. Tight shoulders or jaw. Fatigue. Difficulty concentrating. Changes in appetite. Skin flare-ups. Feeling simultaneously exhausted & unable to shut down. Your body does not divide these into separate little boxes—& neither do I.

🩺At Simply You Integrative Health, we take a whole-person approach to understanding what may be contributing to how you feel & what we can do about it. Comment "destress" below or send us a DM to chat further.