Michael D. Lesem, MD, PA

Michael D. Lesem, MD, PA Dr. Michael Lesem, MD is a solo practitioner Psychiatrist who is Board Certified in Psychiatry and Geriatric Psychiatry.

Michael Lesem, MD PA is a single physician Psychiatric practice located in the Montrose/Museum/Village area in Houston, TX. Dr. Michael Lesem graduated from the University of Texas Medical School, Houston in 1981 where he also completed his Residency in Psychiatry and became Chief Resident. Dr. Lesem is at the forefront of Clinical Research in Mental Health and has worked to destigmatize the illness for over 30 years.

Houston SPRAVATO® (esketamine) Treatment Center
04/07/2026

Houston SPRAVATO® (esketamine) Treatment Center

03/20/2026

For new patient appointments or to schedule a follow up appointment please call, (832) 538-1479x

💭 Spravato vs Ketamine — What’s the difference? (Houston edition)We get this question all the time, so here’s a quick br...
02/01/2026

💭 Spravato vs Ketamine — What’s the difference? (Houston edition)

We get this question all the time, so here’s a quick breakdown:

Spravato®
• FDA-approved
• Nasal spray
• Given in-office with monitoring
• Often covered by insurance
• Used for treatment-resistant depression

Ketamine (IV/IM/lozenge)
• Off-label for depression
• Different forms (IV, injection, oral)
• Typically cash-pay
• May work faster for some people

✨ Both can be effective — the right option depends on your symptoms, history, and what fits your life best.

We’re happy to talk through options and see what makes sense for you or someone you care about here in Houston.
📩 Message us or 📞 call the office to learn more.

💙 Houston friends — we’re accepting new patients!We’re currently welcoming new patients and truly appreciate referrals f...
02/01/2026

💙 Houston friends — we’re accepting new patients!

We’re currently welcoming new patients and truly appreciate referrals from our community. If you know someone in the Houston area who could benefit from thoughtful, compassionate psychiatric care, sending them our way is one of the best ways to help.

📞 Call us(832-538-1479) or 📩 email ([email protected]) us to get started.
Thank you for continuing to trust and support our practice — Houston really does show up for each other.

Campanile South Building (next to The Pit Room)

4306 Yoakum Blvd, Ste 230
Houston, TX 77006

Two Block west of Montrose Blvd

Address

4306 Yoakum Boulevard, Suite 230
Houston, TX
77006

Opening Hours

Monday 9am - 6pm
Tuesday 9am - 6pm
Wednesday 9am - 6pm
Thursday 9am - 6pm
Friday 9am - 2pm

Telephone

+18325381479

Website

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