04/14/2022
Treating stage II re**al cancer
Many stage II re**al cancers have grown through the wall of the re**um and might extend into nearby tissues. They have not spread to the lymph nodes.
Most people with stage II re**al cancer will be treated with chemotherapy, radiation therapy, and surgery, although the order of these treatments might be different for some people. For example, here’s a common approach to treating these cancers:
Many people get both chemo and radiation therapy (called chemoradiation) as their first treatment. The chemo given with radiation is usually either 5-FU or capecitabine (Xeloda).
This is usually followed by surgery, such as a low anterior resection (LAR), proctectomy with colo-a**l anastomosis, or abdominoperineal resection (APR), depending on where the cancer is in the re**um. If the chemo and radiation therapy shrink the tumor enough, sometimes a transa**l resection can be done instead of a more invasive LAR or APR. This might help you avoid having a colostomy. But not all doctors agree with this method, because it doesn’t let the surgeon check the nearby lymph nodes for cancer. Also the radiated re**um does not heal well predisposing you higher rates of wound breakdown
Additional chemo is then given after surgery, usually for a total of about 6 months. The chemo may be the FOLFOX regimen (oxaliplatin, 5-FU, and leucovorin), 5-FU and leucovorin, CAPEOX (capecitabine plus oxaliplatin) or capecitabine alone, based on what’s best suited to your health needs.
Another option might be to get chemotherapy alone first, followed by chemo plus radiation therapy, then followed by surgery.
**alsurgeon