Total Dermatology

Total Dermatology Nissan Pilest, M.D. is a board certified dermatologist dedicated to the art of aesthetic dermatology. Dr. Pilest is a master level injection and laser physician.

He has developed a national reputation with his dermatology practice, treating both medical and cosmetic patients, beginning in 1979. is a Board-Certified Dermatologist with over 38 years experience in Corrective, Cosmetic, and Surgical Dermatology. He is a training physician for Fraxel CO2 Repair Laser, Botox, Juvederm, Restylane, Dysport, Candela Laser and Radiesse. Dr. Pilest is an Assistant Cl

inical Professor of Dermatology at the University of California Irvine; Fellow of the American Society for Laser Medicine and Surgery; Member, American Society of Dermatologic Surgery, Member California Society of Dermatology and Dermatologic Surgery; Member, California Medical Association; Member, Orange County Medical Association; Clinical Trials Physician for SDS Clinical Trials; Past President of the Dermatologic Society of Orange County; OC Top Doctor 2015 and 2016. Dr. Pilest’s practice, Total Dermatology, is recognized as one of Orange County’s most comprehensive laser centers.

A great practitioner never stops learning—even with over four decades of experience, Dr. Pilest continues to sharpen his...
06/01/2026

A great practitioner never stops learning—even with over four decades of experience, Dr. Pilest continues to sharpen his skills! 📝📚 This weekend he attended the “Face to Face Anatomy” course at Allergan’s state-of-the-art AMI Training Center, where he observed a live cadaver dissection in order to continue delivering the safest, most advanced injection techniques. 💉

05/22/2026

Lose it. Tone it. Sculpt it. 💥
This combo works smarter — GLP-1 support paired with EMSCULPT NEO to help reveal a stronger, more defined you.

05/20/2026

POV: your workout clocked in for you today 💅✨

Emsculpt NEO is out here building muscle, burning fat, and giving “I’ve been consistent at the gym” energy… without the gym part 👀🔥

Abs? Snatched.
Glutes? Activated.
You? Booking your next session immediately.

05/18/2026

✨ Lift. Tone. Define. ✨

Meet the treatment everyone’s talking about: EMFACE — the needle-free facial treatment designed to lift skin, smooth wrinkles, and tone facial muscles all at the same time.

Think of it as a workout for your face with zero downtime. 💫

✔️ Lifted appearance
✔️ Smoother skin
✔️ More defined contours
✔️ No needles. No recovery time.

Ready to age smarter, not harder? Schedule your consultation today and let your glow do the talking. ✨

05/01/2026

You gotta do, what you gotta do to get the doctor to film somedays. 🤭

Follow to have fun with us all year!!!

Have you been putting off treating those brown spots until you can afford the downtime? Recovery doesn’t have to involve...
04/30/2026

Have you been putting off treating those brown spots until you can afford the downtime? Recovery doesn’t have to involve taking time off of work or hiding out for days—with our PicoWay laser, achieving clear skin doesn’t mean clearing your schedule! 🗓️

PicoWay delivers 💥 ultra-fast pulses 💥 that create a photoacoustic effect to break down pigment, reducing the thermal impact on the surrounding tissue; this translates to safe yet effective treatment in patients of all skin types and minimal downtime. Most patients will experience mild redness and/or swelling for up to 48 hours after treatment, in addition to darkening of spots that resolve in about a week’s time. 

Don’t postpone your clear skin goals for yet another season, call us at 📞 (949) 727-3800 to schedule a consultation today!

04/27/2026

10/10 would recommend myself 💁‍♂️
💯‼️

04/22/2026

Plated Skin Science harnesses the power of platelet-derived exosomes—tiny cellular messengers that help signal your skin to repair, regenerate, and restore itself.

Think of them as the communication system behind healthier, more youthful-looking skin 👁️

✨ Supports collagen + elastin production
✨ Improves tone, texture, and hydration
✨ Enhances recovery and overall skin quality

This is next-generation skincare designed to work with your skin, not just on it.

Ask us how to incorporate Plated Skin Science into your routine 🤍

DermFavorites

Healthy skin starts with a healthy planet. 🌎✨This Earth Day, we’re mindful of what we put on our skin and how it impacts...
04/22/2026

Healthy skin starts with a healthy planet. 🌎✨
This Earth Day, we’re mindful of what we put on our skin and how it impacts the world around us. From medical-grade skincare to conscious choices, small changes make a big difference—for your glow and the environment.

SPF every day. Recycle your empties. Choose wisely.
Because caring for your skin should never come at the planet’s expense. 💚

02/06/2026

February is about healing, prevention, and renewal.
In honor of Cancer Awareness Month, we’re highlighting Fraxel Dual—an advanced laser treatment clinically shown to reduce precancerous lesions by up to 80%, while also improving sun damage, texture, fine lines, and overall skin health.

✨ February Fraxel Dual Special available
Because prevention is powerful—and confidence is priceless.

📅 Limited time | 📍Book your consultation today

Address

16100 Sand Canyon Avenue, Ste 190
Irvine, CA
92618

Opening Hours

Monday 9am - 5:30pm
Tuesday 9am - 5:30pm
Wednesday 9am - 5:30pm
Thursday 9am - 5:30pm
Friday 9am - 5:30pm

Telephone

+19497273800

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