Felice Gersh MD

06/11/2026

Act Early! Skin aging begins even before you officially reach menopause.

Don’t wait until the damage is visible. By the time menopause is established, significant loss has already occurred—collagen declines, hyaluronic acid diminishes, ceramides drop, and structural fat in the skin recedes. These changes aren’t sudden. They begin years earlier, accelerating through the menopausal transition.

This is not a moment. It’s a process, it’s a decade in motion. And the most rapid shifts often happen in the final years before menopause is officially defined.

Act early. Protect your skin health before depletion begins. For most women, hormone therapy is a key part of that strategy, unless a true contraindication exists. Preservation always outperforms repair.

Learn more, watch my full talk,
Why menopause accelerates wrinkles:
Tips to keep your skin healthy & vibrant
https://youtu.be/J1aOzOcrlqg

06/11/2026

Why aim for menopausal hormone levels that resemble those of a younger woman? Because your cells don’t track birthdays. Biology doesn’t read calendars. Most cells in the body are constantly turning over: living, dying, and being replaced in a continuous cycle.

Old cells are cleared away. New ones are born from stem cells. And when a new bone cell appears, it has no idea whether you’re 25 or 55. It only knows the signals it receives and the environment it enters.

Give that cell the right conditions, and it performs optimally. Nutrients. Signals. Hormones. Physiology responds to inputs. Provide hormone levels consistent with healthy biology, and cells will do what they were designed to do.

Learn more, watch my full talk,
Hormone therapy dosing in menopause:
Why the “lowest dose” approach is wrong
https://youtu.be/hTLyLLOZYnU

06/10/2026

Levels matter & hormone therapy is about more than stopping hot flashes

For years, conventional guidance said hormone levels didn’t matter. Use the lowest dose that stops hot flashes and night sweats—that was the goal. Symptom relief became the endpoint. But symptoms are only one small piece of physiology.

If you care about optimizing long-term health, the conversation changes. The cardiovascular system matters. The musculoskeletal system matters. The brain matters. Hormones influence all of them.

That’s why measuring levels is essential. The aim isn’t simply comfort—it’s physiology. Restoring estradiol to levels that approximate those seen in younger, healthy women supports systems that depend on it. Not minimal relief. Meaningful restoration.

Learn more, watch my full talk,
Hormone therapy dosing in menopause:
Why the “lowest dose” approach is wrong
https://youtu.be/hTLyLLOZYnU

06/10/2026

Yes, dose matters because levels matter. I know this is controversial in many circles, but estradiol’s effectiveness changes depending on dose.

What is the optimal dose of estradiol? The better question is: what level do you achieve? Dose alone doesn’t tell the story. Physiology responds to the hormone circulating in the bloodstream, not the number printed on the patch.

Transdermal delivery adds complexity. Skin wasn’t designed to deliver hormones. It evolved to keep things out, not usher molecules in. That’s why responses vary. The same patch can produce very different blood levels from one woman to the next.

Early approval studies of Estradiol transdermal patch showed this clearly. Only the highest strength—0.1 mg—consistently pushed estradiol levels toward about 100 picograms per milliliter, a range associated with meaningful bone protection.

Learn more, watch my full talk,
Hormone therapy dosing in menopause:
Why the “lowest dose” approach is wrong
https://youtu.be/hTLyLLOZYnU

06/06/2026

My latest talk:
Intermittent Fasting Mistake: Don’t Skip Breakfast
https://youtu.be/8t0Lj85dyKY

A lot of women think they are doing intermittent fasting correctly by skipping breakfast and waiting until 1 or 2 PM to eat. But Dr. Gersh explains why that may be the wrong fasting window for human biology. Your body is programmed to process food better earlier in the day, when insulin sensitivity, digestion, mitochondrial function, and metabolic rhythms are working in your favor.

Have you been skipping breakfast because you think that is the heal...

06/06/2026

My latest talk:
Veozah & Cancer Risk: What menopausal women with hot flashes should know
https://youtu.be/ItBMiRVcy1w

A newer hot flash medication called Veozah is being widely discussed as a non-hormonal option for menopause. But a recent 2026 paper raises questions about possible cancer-related safety signals. This does not prove the drug causes cancer, but it does mean women deserve to understand the risks, the mechanism, and why long-term safety data matters.

Veozah, also known as fezolinetant, is a newer non-hormonal medicat...