Dr. May

03/30/2026

Buying your peptides online? Buyer beware!

A peer-reviewed study published in Drug Testing and Analysis found that 65% of online peptide products tested had endotoxin levels far exceeding safe thresholds for human injection.

If you've heard the buzz about BPC-157, TB-500, or peptide therapy for healing injuries, boosting recovery, or reversing aging; this episode is essential vie...

03/25/2026

Each mushroom has it's own unique profile or phenotype. Check them out!

03/25/2026

This is a great review of the study on meat consumption associated with slowing down dementia risk. Worth the read!

This cohort study investigates the association of meat consumption with risk of cognitive decline and dementia among older adults with APOE genotypes ε3/ε4 and ε4/ε4.

03/23/2026

YOUR GUT IS CONTROLLING YOUR TESTOSTERONE — HERE'S THE SCIENCE

A 2025 systematic review in PeerJ mapped out the gut-testosterone connection in men for the first time. The findings are massive: specific gut bacteria like Ruminococcus and Acinetobacter directly correlate with higher testosterone levels, while dysbiosis tanks your hormones through the HPG axis.

Your gut microbes literally regulate how much testosterone your body produces. 🧬🔬

This changes the game for men's health. Probiotics, prebiotics, and dietary interventions are now being studied as legitimate strategies to optimize testosterone — not just supplements and injections.

A healthy gut isn't just about digestion. It's about maintaining the hormonal foundation that drives everything from muscle growth to mental clarity. 💪

You can't out-supplement a broken gut. Fix the foundation first.



📖 Source: PeerJ (2025) — "Potential relationship of the gut microbiome with testosterone level in men: a systematic review" DOI: 10.7717/peerj.19289

03/22/2026

TESTOSTERONE + RESISTANCE TRAINING = THE ONLY COMBO THAT ACTUALLY WORKED IN FRAIL MEN

A 2024 follow-up of a randomized clinical trial in The Aging Male studied 148 men over 70 with low testosterone and mobility problems. Four groups: testosterone alone, resistance training alone, both combined, or nothing. After 20 weeks and a 1-year follow-up, only the combination group showed significant improvements — better chair stand performance (p=0.001) and reduced fatigue compared to controls. Neither intervention alone moved the needle. 🔬💪

This is critical for every aging man and their clinicians to understand. Testosterone replacement without training doesn't build functional strength. Training without adequate testosterone can't overcome the hormonal deficit. You need both pillars working together to fight age-related decline effectively. 🏋️

Half measures get half results. Stack the protocol or don't bother.



📖 Source: The Aging Male (2024) — "Testosterone and resistance training improved physical performance and reduced fatigue in frail older men: 1 year follow-up of a randomized clinical trial" PMID: 39289825

03/22/2026

📌 METABOLIC MONDAY

ULTRA-PROCESSED FOODS ARE WRECKING YOUR METABOLISM — AND YOUR TESTOSTERONE

A controlled crossover trial published in Cell Metabolism (2025) put men on ultra-processed vs. unprocessed diets and measured the damage. The result? Ultra-processed food independently increased body weight and tanked the LDL-to-HDL ratio — regardless of how many calories were consumed. This wasn't about eating too much. It was about eating the wrong things. 🔬

For men trying to optimize metabolic and hormonal health, this is a wake-up call. That "convenient" diet of packaged foods isn't just adding body fat — it's actively disrupting your lipid profile and reproductive fitness. The industrial food system is not designed to keep you healthy. 💪🔥

Still think your frozen meals are "good enough"? Your bloodwork disagrees.



📖 Source: Cell Metabolism (2025) — "Effect of ultra-processed food consumption on male reproductive and metabolic health" DOI: S1550-4131(25)00360-2

03/21/2026

📌 WEEKEND WARRIOR

MICROPLASTICS WERE FOUND IN 100% OF HUMAN TESTICLES TESTED

In 2024, researchers at the University of New Mexico tested human testicular tissue and found microplastics in every single sample — 100% of the 23 men tested. These aren't abstract environmental concerns anymore. Plastic particles are physically lodged in your reproductive organs, leaching BPA and phthalates that mimic estrogen, suppress testosterone production, and damage s***m quality through oxidative stress and HPG axis disruption. 🧪⚠️

The data on exposure is staggering: phthalate metabolites have been found in 75% of Americans, and BPA in 90% of urine samples tested in the US, Germany, and Canada. These chemicals are in your food packaging, water bottles, receipts, and personal care products. For men, this is a direct assault on hormonal health that compounds daily. 🛡️

You can't eliminate every exposure. But you can stop microwaving plastic, ditch the BPA-lined cans, and start filtering your water. Your te**es are under siege.



📖 Source: Toxicological Sciences (2024) — University of New Mexico study on microplastics in human and canine testicular tissue

03/20/2026

📌 FORGED FRIDAY

MUSCLE STRENGTH PREDICTS WHETHER YOU LIVE OR DIE — EVEN PAST 90
A massive 2024 prospective cohort study across 28 countries found that grip strength is inversely and dose-dependently associated with all-cause mortality — even in men over 90 years old. There's no threshold. No plateau. Every incremental gain in strength lowers your risk of death. Period. This wasn't a small study — it tracked 725 of the oldest men alive. 🏋️💀

This is the most powerful argument for resistance training ever published. It doesn't matter if you're 30 or 90 — building and maintaining muscle strength is the single best predictor of how long you'll live and how well you'll function. Strength isn't vanity. It's survival. 🔥

The barbell doesn't care how old you are. And neither does mortality.



📖 Source: J Cachexia Sarcopenia Muscle (2024) — "Association of Muscle Strength With All-Cause Mortality in the Oldest Old: Prospective Cohort Study From 28 Countries" PMID: 39439054

03/19/2026

📌 THRIVE THURSDAY

SLEEPING LESS THAN 6 HOURS? YOU'RE CHEMICALLY CASTRATING YOURSELF
A 2024 study in Andrology using NHANES data from over 9,000 participants confirmed what the research has been screaming: sleep deprivation destroys testosterone. Men with obstructive sleep apnea had testosterone levels nearly 40% lower than controls (13.1 vs. 21.8 nmol/L). And it's not just OSA — even one week of sleeping 5 hours per night drops testosterone by 10-15%, equivalent to aging 10-15 years overnight. 😴🔻

Sleep isn't a luxury — it's the single most powerful hormone optimization tool you have. Your testosterone follows a circadian rhythm that's entirely sleep-dependent, requiring at least 3 hours of quality sleep with normal architecture just to initiate the nightly surge. Every hour you sacrifice to Netflix or your phone is hormonal capital you'll never get back. ⏰

You want to optimize your hormones? Start by turning off the screen and going to bed.



📖 Source: Andrology (2024) — "Association of sleep duration and quality with serum testosterone concentrations among men and women: NHANES 2011-2016" DOI: 10.1111/andr.13496