06/16/2026
The question isn’t “Which weight-loss medication is best?”
That’s the question social media asks.
The question medicine asks is:
Which medication has the strongest evidence for the diseases this patient actually has?
We’re no longer treating weight in isolation.
We’re treating cardiovascular disease, chronic kidney disease, type 2 diabetes, sleep apnea, fatty liver disease, and obesity—all at the same time.
The future of medicine isn’t about chasing the biggest weight-loss number.
It’s about matching the right therapy to the right patient at the right time.
That’s where the science is headed.
And honestly, it’s about time.
— Tyler Perrin-Bellelo, MD, FACP, D-ABOM
Internal Medicine | Obesity Medicine