Psychedelics Transdiagnostic Therapeutics

09/23/2026

Can a new name change how we understand psychedelic medicine? The term “psychoplastogen” emphasizes a drug’s potential to promote neural plasticity, often without the psychedelic experience. It is an intriguing area of research, but the terminology alone cannot answer the questions that matter most: Does the treatment work? For whom? And what does the evidence show about its safety?

In my latest article, I examine the science, the commercial appeal, and the limits of rebranding a complex field.

👉 Read the article here: https://drnair.substack.com/p/psychoplastogens-why-neologistic

The psychedelic industry has come up with a new word: psychoplastogen.

08/19/2026

Nearly half of U.S. veterans with problematic substance use report significant loneliness. That finding raises an important question: Are we paying enough attention to connection and purpose when we talk about mental health and substance use?

Loneliness is more than simply being alone. For veterans experiencing psychological distress, trauma, depression, or problematic substance use, a loss of meaningful connection and purpose may become part of a much larger clinical picture.

This is also where emerging research into psychedelic-assisted therapy becomes particularly interesting. Studies are exploring psychedelic-assisted approaches for conditions including PTSD, depression, and substance use disorders. While psychedelics should not be viewed as a treatment for loneliness itself, researchers are increasingly interested in experiences often reported in psychedelic therapy, including shifts in perspective, connectedness, emotional processing, and meaning.

For veterans, this raises a compelling area for continued research: Could treatments that address psychological distress while helping individuals reconnect with meaning, relationships, and a sense of purpose become an important part of more comprehensive care?

The future of mental health treatment may require us to look beyond symptoms alone and consider something deeply human: our need for connection, belonging, and purpose.

🔗 https://pubmed.ncbi.nlm.nih.gov/41656555/

07/02/2026

Physician Addiction Evaluations for Attorneys With Mohan Nair, M.D.
Expert Psychiatric Evaluation & Consultation in Cases Involving Physician Addiction, Professional Impairment, and Substance Use Disorders.

🧠 Learn more: https://open.substack.com/pub/drnair/p/physician-addiction-evaluations-for?r=11fx3g&utm_campaign=post-expanded-share&utm_medium=web

06/15/2026

Is Autism a Risk For S*xual Deviance?

🔗 Read the full article & subscribe on substack:
https://open.substack.com/pub/drnair/p/is-autism-a-risk-for-sexual-deviance?r=11fx3g&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

06/05/2026

Does Robert Bales Deserve a Second Chance? Shortly after midnight on March 11, 2012, U.S. Army Staff Sergeant Robert Bales left his base in Afghanistan and walked to nearby villages, where he killed 16 Afghan civilians, including eight children. To avoid the death penalty, Bales later pleaded guilty to the murders and was sentenced to life in prison without the possibility of parole. The crimes shocked the world and remain one of the darkest chapters of the Afghanistan War.

Read the full article here:

Shortly after midnight on March 11, 2012, U.S.

05/28/2026

Emerging research continues to deepen our understanding of how repetitive head impacts may influence neurological health over time. This new study published in JAMA Neurology explores the association between soccer heading exposure and changes in blood biomarkers linked to neural injury and neurodegeneration. An important contribution to the ongoing conversation surrounding brain health, sports medicine, and long-term neurological outcomes. ⚽🧠

🔗 Read the study here: https://jamanetwork.com/journals/jamaneurology/article-abstract/2849324

05/26/2026

The Garden Grove Methyl Methacrylate Incident: A Medical-Legal Neurotoxicology Perspective” By Mohan Nair, MD — with toxicology commentary from Ashok Kumar Jain, M.D., FACEP.

Why the real public-health threat may not be the chemical in the tank but the litigation, the media cycle, and the mass psychogenic illness that follows it.

Explore the broader medical-legal implications of the Garden Grove incident in my recent article:

A Medical-Legal Neurotoxicology Perspective By Mohan Nair, M.D. — with toxicology commentary from Ashok Kumar Jain, M.D., FACEP.

05/19/2026

Exploring the intersection of forensic psychiatry, neurodevelopmental vulnerability, compartmentalization, and the psychology of violent offenders. In my latest article, I examine the complex clinical frameworks surrounding Autism Spectrum Disorder (ASD), serial sexual homicide, and high-profile cases including Rex Heuermann and Bryan Kohberger, while emphasizing the critical distinction between vulnerability and causation.

Callous-unemotional loading: Affective flatness, lack of visible distress in custody, and the planning sophistication alleged by the prosecution

Kohberger reportedly experienced Visual Snow Syndrome: a persistent perception of static or flickering noise across the visual field, accompanied by tinnitus and a sense of detachment from reality — which, taken together with his documented Autism Spectrum Disorder diagnosis, is suggestive of weak central coherence and aligns with features seen in ASD.

Read the full article & subscribe on Substack: https://open.substack.com/pub/drnair/p/rex-heuermann-bryan-kohberger-and?r=11fx3g&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

04/30/2026

I, Mohan Nair, MD have spent several decades studying sexual deviance and violent sexual offending - writing , presenting and testifying in Court on this matter.

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I, Mohan Nair, MD spent several decades studying sexual deviance and violent sexual offending - writing , presenting and testifying in Court on this matter.

04/21/2026

In the early hours of March 11, 2012, under the cover of darkness in rural Afghanistan, U.S. Army Staff Sergeant Robert Bales walked off base and into history. By sunrise, 16 Afghan civilians were dead. Among them were women and children.

What followed was swift and definitive: Bales was charged, convicted, and sentenced to life in prison without parole. The narrative seemed clear—a soldier turned mass murderer.
But is that the full story? Or is it the version we are most comfortable accepting?

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In the early hours of March 11, 2012, under the cover of darkness in rural Afghanistan, U.S.