06/24/2026
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What is the mortality gap?
The mortality gap refers to the decreased life expectancy observed for people with schizophrenia, compared to the general population. People with schizophrenia are estimated to have a life expectancy that is 15-20 years shorter than the general population.
What drives the mortality gap?
While people with schizophrenia are more likely to die from non-natural causes like injury and su***de, the largest driver of the mortality gap is thought to be untreated or undertreated physical health conditions like cardiovascular disease, respiratory disease, and cancer. The elevated likelihood of dying from treatable physical health conditions is especially alarming.
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Here we share recent research into the increased risk of mortality for people with schizophrenia compared to the general population.