06/01/2026
Thinning hair with age? The reason goes deeper than your scalp.
To grow hair, your follicles need to stay in their growth phase. As we age, that phase gets shorter, so hair comes in finer and sheds sooner.
One molecule helps keep follicles growing: spermidine. In a placebo-controlled trial of 100 people, the spermidine group had 52% more follicles in their active growth phase, and zero shedding at six months.
It works by supporting autophagy, your cells’ renewal process that naturally slows with age.
And the form matters. Food-derived spermidine comes with its full pool of polyamines for your body to work with. Synthetic is just the isolated molecule.
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