09/08/2026
Musculoskeletal pain is one of the most common complaints among women in perimenopause and menopause, yet it remains underrecognized and frequently mischaracterized. Women often present with shoulder pain, hip stiffness, tendon discomfort, or diffuse joint aches without a clear history of injury.
These symptoms are typically approached as isolated orthopedic conditions. However, the timing, progression and systemic nature of these presentations suggest a broader physiologic origin.
Increasing evidence supports that musculoskeletal symptoms in midlife are influenced by hormonal decline, inflammatory changes, metabolic dysfunction, and alterations in nervous system regulation. Recognizing this interconnected physiology is essential for accurate diagnosis and effective treatment.
Learn more: https://ow.ly/Y3Jp50ZL3La
Learn how estrogen decline, inflammation, and metabolic shifts drive midlife female musculoskeletal pain, requiring a systems-based clinical care approach.