08/13/2026
When nurses at St. Jude encounter challenges at the bedside, they ask questions, seek evidence and help create new approaches to care.
This is how Brittany Bedard, RN, approached the clinical challenge of esophageal mucositis, a painful side effect of radiation therapy. Bedard is used to going above and beyond to help her patients through cancer treatment while also preserving their quality of life. But, as she looked for ways to address esophageal mucositis, she discovered there was little research to inform care.
Bedard knew that her colleagues at St. Jude regularly used photobiomodulation, commonly referred to as “red light therapy,” to prevent and mitigate oral mucositis in patients undergoing bone marrow transplantation. So, she partnered with Belinda Mandrell, PhD, RN, and Hannah Clugh, RN, in the Division of Nursing Research to explore whether the therapy could help with esophageal mucositis, too.
“When the type of tumor is so rare and the treatment is so rare, it went from ‘What can I find?’ to ‘If it’s not going to hurt, why not try?’” Bedard said.
Together, they designed a protocol tailored to the needs of Bedard’s patient, adapting existing technology and drawing on years of nursing research expertise. Throughout treatment, the patient maintained their weight, continued eating normally and experienced minimal pain, showcasing that photobiomodulation could help.
The project reflects how research at St. Jude often begins with questions raised during patient care. It also highlights the support available to nurses who want to investigate ways to improve outcomes.