06/09/2026
One of the most common questions we hear from people considering ketamine therapy is simple:
"Do I need to stop my antidepressants first?"
For many patients, the answer may be no.
A recent study of more than 300 patients found that ketamine and Spravato treatment outcomes were similar whether patients were taking SSRIs, SNRIs, other antidepressants, or no antidepressants at all.
That's important because it means exploring ketamine treatment doesn't necessarily require starting over with your current medication plan.
Every patient is different, and medication decisions should always be made with your provider. But the research offers reassuring news for people who have already spent years navigating medication changes and are looking for another option.
Read our latest article to learn more: https://newpathwaysclinic.com/do-you-need-to-stop-antidepressants-before-ketamine-therapy/