10/18/2021
15 million Americans routinely take PPIs. As many as 10.5 million people take PPIs even when they shouldn't. I’ve covered the topic of Acid reducers before. Although they may be necessary at times, you ultimately should try to find the CAUSE of your symptoms, rather than just covering them up with medications that may cause other issues.
The original article that piqued my interest for this email, Stomach Acid & Heartburn Drugs Linked with COVID-19 Outcomes, did not offer any solid conclusion. I searched a little longer and found this one, Mixed Bag for PPI Use and COVID-19 Infection, Severity. After looking around on PUBMED for a while the only conclusion you can reach is that there is somewhat of an increased risk for people that use PPI medication to have a more severe reaction to a Covid 19 infection.
I will suggest you read the articles if you want more details but here are the basics that you should understand, if you are dealing with Acid reflux/GERD and are taking PPI’s.
First of all, the most common reason for acid reflux is a LOW production of your own natural stomach acid HCL. If you generally have low stomach acid, the valve that separates your esophagus from your stomach the LES (lower esophageal sphincter) can become weak because there isn’t enough acid regularly stimulating the valve and keeping it strong. Just like any muscle, if it stops being challenged it becomes weaker. The consequence of this valve weakening is that when you lie down at night the stomach acid that you do produce can leak up to your esophagus and cause heartburn. Also after a meal when you produce slightly higher amounts of acid and your stomach is full the acid may “bubble-up” and escape up to the esophagus.
The traditional medical treatment for this is to suppress the acid so you feel better. It makes sense, but decreasing the natural acid in your stomach means 2 things. One, that you are less able to digest foods, which need the acid to break them down. Two, that you decrease your ability to fight infection. In this specific case, the low stomach acid changes the acid base balance of the resat of your intestinal tract and allows for unfriendly microbes to live where they would normally be killed off by the acid.
Sorry for all you long-term Newsletter readers that had to read that again, but it’s necessary info.
Now here is how that situation which may be encountered by up to 15 million Americans taking PPI medications, mainly Prilosec and Nexium, plays out with COVID 19. Since 80% of the health of your immune system is dependent on the health of your GUT HEALTH, you may have a more difficult time managing COVID -19. This could be because your immune system isn’t strong enough to deal with the infection, or could be just as likely to trigger an overreaction of your immune system as well. Both can lead to severe symptoms.
So what do you do if you suffer from indigestion, acid reflux, heartburn, GERD? You do your best to address the CAUSE. Check out the three videos I created on my YouTube channel The Digestion Diaries, to learn more. If you are already taking a PPI, speak to your prescribing doctor because the research leans heavily toward H2 blockers being a safer option, and TUMS, which is basically calcium, the safest of them all.
As always, I will always state that there is a risk/benefit ratio for each individual and sometimes there are situations where PPI’s are the best option for you. Since SO MANY PEOPLE take these medications and MOST doctors DO NOT ask the simple question WHY do you need this medication, I had to write this email today. ( BTW got really confused about whether to put a “?” back there, don’t ask me for grammar lessons).
What you can ask me for is help to figure out WHY you have the health issues you do. The WHY is the most important question to answer. If you aren’t taking any of these meds then pass this on to someone you know that is, I bet there’s at least one.
Reach out with any questions!
Small meta-analysis with varying conclusions emphasizes need for more research