10/12/2026
ESTROGEN DOES MORE THAN REGULATE YOUR PERIOD. IT REGULATES YOUR FAT.
And NO, I’m not just talking about weight gain during menopause.
A review published in Nature Reviews Endocrinology explains how estrogen influences adipose tissue at the cellular level.
Estrogen regulates insulin sensitivity, inflammatory signaling, mitochondrial function, and WHERE we store fat.
As estrogen declines, women tend to accumulate more visceral fat, the fat surrounding our internal organs, which is associated with increased cardiometabolic risk.
And here’s what I want women to understand:
You can experience important changes in body composition WITHOUT dramatic changes on the scale.
This is why I insist on measuring body composition rather than relying exclusively on weight or BMI.
And yes, hormone therapy may help with some of these metabolic changes, but it is NOT a substitute for nutrition, strength training, or individualized medical care.
Menopause is a METABOLIC transition. We need to start treating it as one.
Strong over skinny. ALWAYS.
Dr. Rocío Salas-Whalen
Source: Vieira-Potter et al. Nature Reviews Endocrinology (2026). DOI: 10.1038/s41574-025-01180-2