InnerMost PBC

InnerMost PBC InnerMost is New York’s premier Psychedelic Therapy Innovation Center—bringing treatment, training, & research to Manhattan ✨

In his latest Substack piece, Dr. Casey Paleos asks the question the field has been avoiding: what if our patients aren'...
07/23/2026

In his latest Substack piece, Dr. Casey Paleos asks the question the field has been avoiding: what if our patients aren't treatment-resistant? What if instead, the treatments are failing them?

Read the full piece, comment, and subscribe here: https://caseypaleosmd.substack.com/p/symptoms-are-signals

We're excited to share that InnerMost's Co-Founder and Chief Medical Officer, Dr. Casey Paleos, has launched Much Ado Ab...
06/09/2026

We're excited to share that InnerMost's Co-Founder and Chief Medical Officer, Dr. Casey Paleos, has launched Much Ado About Nuance—a Substack exploring the science, philosophy, and human stories behind psychedel*c medicine and what it takes to do this work well.

The first post is live. Subscribe here: https://caseypaleosmd.substack.com/subscribe

Stay tuned for his next post features a conversation with Hadas Alterman, JD—one of the leading legal voices in the psychedelic space—discussing the recent psychedel*c medicine Executive Order.

What if the archetypal figures and symbols in your psychedel*c experiences were trying to tell you something?Join us in ...
05/28/2026

What if the archetypal figures and symbols in your psychedel*c experiences were trying to tell you something?

Join us in Gramercy on Friday, June 12 · 7–9:30 PM for an evening with Simon Yugler, psychedel*c therapist and author of Psychedel*cs and the Soul, as he introduces the Mythopoetic Integration method—a depth psychology-based framework for working with the symbolic dimensions of nonordinary states.

Following a lecture by Simon, experience a live demo, participate in a Q&A discussion, and enjoy time for socializing with our amazing community. ​This event is designed for therapists, facilitators, and clinically informed explorers. All are welcome.

Spots are limited. Register here: https://luma.com/simonyugler61226

InnerMost is located at 137 E 25th St., NYC. The 6 train stops at 23rd St. (~5-min walk) and the N, R, and W trains also stop at 23rd St (~10-min walk).

The legal ground beneath psychedelic practice is shifting, and we have an opportunity to make sense of it together.Join ...
05/13/2026

The legal ground beneath psychedelic practice is shifting, and we have an opportunity to make sense of it together.

Join us on Wednesday, June 3rd from 7–9:30pm at InnerMost in Gramercy, NYC, for an intimate clinician mixer with Hadas Alterman, JD—one of the leading legal voices in the psychedelic space. We'll be unpacking the recent psychedelic medicine executive order and what the rapidly evolving federal landscape means for practitioners working in this field.

Space is limited—RSVP here: https://luma.com/innermost-hadas-alterman

04/27/2026

Ketam*ne is a promising tool in psychedel*c-assisted therapy, and it's also a substance that can cause dependence and harm. Both things are true, and the field can't afford to look away from either.

At last week's InnerMost Mixer in Gramercy, Andrew Tatarsky, PhD and Casey Paleos, MD sit with that paradox. Integrative Harm Reduction Psychotherapy doesn't pretend this tension doesn't exist, it's about holding it with honesty and highly personalized care.

The evidence is there: psychedel*cs, used in the right set and setting, with the right therapeutic container can help people address the root of what's driving their suffering—even harmful relationships with substances. This work requires a clinical lens that centers the whole person.

This fall, Andrew and Casey are bringing that lens into a three-day training at InnerMost. If this conversation is one you want to be part of, share your interest here: https://forms.gle/qhuS4HEPNkFV2dVd7

During last week's InnerMost Mixer, we had the pleasure of sitting down with Andrew Tatarsky, PhD—founder of Integrative...
04/27/2026

During last week's InnerMost Mixer, we had the pleasure of sitting down with Andrew Tatarsky, PhD—founder of Integrative Harm Reduction Psychotherapy—for an intimate fireside chat and Q&A with ~40 clinicians who attended.

Casey and Andrew explored some of the most pressing questions at the intersection of harm reduction and psychedelic-assisted therapy: what the disease model gets wrong about addiction, why people develop drug solutions rather than drug problems, the deep philosophical alignment between IHRP and psychedelic work, and what the field still needs to figure out about treating people who have both a psychedelic therapy indication and a complex relationship with substances.

If the conversation left you wanting more: this fall, InnerMost is hosting a three-day clinical training with Andrew Tatarsky, PhD and Casey Paleos, MD diving deep into IHRP and psychedelic-assisted therapy. Space is limited to 50 participants and we expect it to fill quickly. Share your interest: https://forms.gle/CqBJpksFigkfWcK1A

On April 18th, President Trump signed an executive order to dramatically accelerate access to new medical research and t...
04/20/2026

On April 18th, President Trump signed an executive order to dramatically accelerate access to new medical research and treatments based on psychedel*c therapies, directing the FDA to fast-track review of compounds like ps*locybin and iboga*ne.

The FDA will issue national priority vouchers for three psychedel*cs, potentially cutting review timelines from months to weeks. This is the first time it has ever fast-tracked any psychedel*c substance. The science has been building for years, and now the regulatory environment is beginning to catch up.

We've been preparing for this moment at InnerMost. Ketam*ne-assisted therapy is already here, but we've always known it was just the beginning. That's why treatment is one of our core pillars, and training and clinical research exist alongside it. The arrival of new psychedel*c therapies won't just require access, it will require providers who are prepared, protocols that are evidence-based, and a field that can scale responsibly.

We’re excited to share the new date for our rescheduled event ✨We’re hosting an intimate evening with Olga Naiman—author...
04/15/2026

We’re excited to share the new date for our rescheduled event ✨

We’re hosting an intimate evening with Olga Naiman—author of Spatial Alchemy: Design Your Home to Transform Your Life and the designer behind InnerMost’s NYC space—for a conversation on set and setting and the role of environment in healing. Co-hosted with our friends at Psychedelic Assembly.

From psychedelic therapy to everyday life, the spaces we inhabit shape how safe, open, and regulated we feel. Olga will share how intentional design—through color, texture, and symbolism—can support transformation.

Date: May 6 (Wed)
Time: 7:00 – 9:30 PM
Location: InnerMost, 137 E 25th St., 11th Fl., NYC

✨ RSVP via the link in bio—we’d love to have you there!

At InnerMost, we’re building something that goes far beyond a clinic. We're building a community hub where patients, cli...
04/14/2026

At InnerMost, we’re building something that goes far beyond a clinic. We're building a community hub where patients, clinicians, and collaborators come together around a shared commitment to healing, integrity, and growth.

Whether you’re seeking support through ketam*ne- or Spravato-assisted psychotherapy, a clinician looking to deepen your work, or a partner interested in shaping the future of the field, we welcome you.

If you’ve been curious about what we’re building, we’d love to stay in touch. Sign up for our newsletter, check out our upcoming events, or schedule a discovery call via our Linktree: https://linktr.ee/innermost.one

Join us for our next InnerMost Mixer for clinicians, featuring Andrew Tatarsky, PhD on Wednesday, April 22 at 7:00pm in ...
04/09/2026

Join us for our next InnerMost Mixer for clinicians, featuring Andrew Tatarsky, PhD on Wednesday, April 22 at 7:00pm in Gramercy.

Dr. Tatarsky is a clinical psychologist and developer of Integrative Harm Reduction Psychotherapy (IHRP) with over four decades of experience.This month’s conversation will explore psychedel*cs and substance use disorder, examining how harm reduction and emerging psychedel*c therapies can expand more compassionate, flexible approaches to care.

Dr. Tatarsky will join InnerMost's Chief Medical Office, Casey Paleos, MD for a fireside chat, followed by time to connect with fellow clinicians and providers across NYC.

RSVP via https://luma.com/gd89aega ✨

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