The Mindich Child Health and Development Institute

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The Mindich Child Health and Development Institute

The Mindich Child Health & Development Institute is a research enterprise whose mission is to advance knowledge & therapies for diseases affecting children

The Mindich Child Health and Development Institute is a translational research enterprise with the mission of advancing knowledge and therapies for diseases affecting infants, children, and adolescents. Led by Bruce D. Gelb, MD, the MCHDI provides an intellectually rich and supportive environment for fostering collaborative scientific investigation and Mount Sinai’s “bench to bedside” philosophy,

as well as training the next generation of scientific leaders in pediatric medicine. Physician-scientists and scientists at the MCHDI work in a multidisciplinary manner with researchers and physicians in various departments and institutes at Mount Sinai. Together, we strive toward the objectives of developing robust paradigms for understanding the effects of genetics and environment on the health of infants, children and adolescents, and personalizing pediatric medicine through genetics and genomics. Our main areas of research focus include:

-Allergy & Asthma
-Cardiovascular Disease
-Neurodevelopmental Disorders
-Obesity & Diabetes

For a full list of our faculty members please visit:

http://icahn.mssm.edu/research/institutes/child-health-and-development-institute/team

05/29/2026

Effects of early to

Megan Horton, PhD, discusses her research combining naturally shed baby with advanced imaging to pinpoint specific weeks during and infancy when the developing brain appears most vulnerable to .

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Scientists found that toxic metal exposures during specific time windows increased the risk of brain and mental health symptoms a decade later.

05/22/2026

Psychotropic Prescribing in : Balancing Teratogenic Risk and Relapse Prevention

Veerle Bergink, MD, PhD, discusses the pharmacological management of severe illness during pregnancy and the period, with emphasis on relapse prevention, as presented at the American Psychiatric Association 2026 meeting.

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Planning for prevention of perinatal psychiatric relapse with safer medication options.

05/07/2026

Liver and Muscle Cells Influence Following

Brian Brown, PhD, Joshua Brody, MD, and Sophia Siu, an MD/PhD student at the Icahn School of Medicine at Mount Sinai, discuss their research overturning a longstanding assumption about how mRNA vaccines generate immunity, revealing that certain non-immune cells help determine vaccine effectiveness.

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A study showed that non-immune cells shape mRNA vaccine responses. Expression of mRNA in muscle cells increased immunity, while expression in the liver reduced it. The findings could have broad implications in vaccines, oncology, and autoimmunity.

05/01/2026

Surprising links between , 's could change how we treat both

Joseph Buxbaum, PhD, discusses his research on the potential connection between autism and Alzheimer’s.

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The idea that two conditions at opposite ends of life might be biologically linked is beginning to upend long-standing assumptions in brain science, blurring a divide that has shaped the field.

04/24/2026

New Study Reveals Why Commonly Starts in

Shruti Naik, PhD, and Emma Guttman, MD, PhD, detail their recent study which sheds new light on the biological mechanisms that underlie the early onset of eczema in childhood.

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In a groundbreaking study published in Nature on February 25, 2026, scientists from the Icahn School of Medicine at Mount Sinai, Weill Cornell Medicine, and collaborating institutions have shed new

04/03/2026

Icahn School of Medicine at Mount Sinai Awarded $8.2 Million Grant to Investigate the Origins of Blood-Forming

Christopher M. Sturgeon, PhD, and researchers at the Icahn School of Medicine at Mount Sinai have been awarded an $8.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate the earliest developmental origins of the system.

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Researchers at the Icahn School of Medicine at Mount Sinai have been awarded an $8.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate the earliest developmental origins of the hematopoietic system—the network of organs and tissues ...

03/27/2026

medication may reduce later risk of , study finds

Jeffrey Newcorn, MD, discusses a study finding that the stimulant methylphenidate, including drugs such as Ritalin and Concerta, may lower the risk of psychosis when prescribed to younger with ADHD.

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Prior research had suggested a possible link between stimulants prescribed for ADHD and psychotic disorders such as bipolar.

03/19/2026

likely have more ‘forever ’ in blood than thought

Shelley Liu, PhD, discusses her research finding that born between 2003 and 2006 were exposed to far more “forever chemicals” before birth than scientists previously understood.

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US test of 120 umbilical blood cord samples identified 42 Pfas compounds, which do not naturally break down

03/05/2026

Exclusive: First test of therapy for rare form of is underway

Alexander Kolevzon, MD, discusses the Jaguar Gene Therapy study he is leading to test a novel gene therapy targeting a rare genetic form of autism spectrum disorder.

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Two years ago, a small biotech startup got permission to test a gene therapy for a rare and disabling form of autism. The plan: Deliver a gene that’s vital for ...

02/20/2026

Study finds to dozens more than previously detected in cord blood

Shelley Liu, PhD, discusses her research finding that born between 2003 and 2006 were exposed to far more “forever ” before birth than scientists previously understood.

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Nontargeted analysis identified 42 PFAS in cord blood, revealing broader prenatal exposure than traditional testing methods capture.

Address

1470 Madison Avenue
New York, NY
10029

Website

http://icahn.mssm.edu/research/institutes/child-health-and-development-institute

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