06/03/2026
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a liver condition that used to be referred to as nonalcoholic fatty liver disease or fatty liver disease. MASLD is a liver condition in which excess fat accumulates in the liver.
MASLD is more common in people with Down syndrome, possibly because of differences in metabolic function in people with Down syndrome compared to people without Down syndrome. Additionally, some of the conditions (such as obesity) that increase the risk of MASLD are more common in people with Down syndrome. There are lifestyle choices that can reduce the risk of MASLD and treat MASLD, including:
▪ Losing weight (if the person is overweight or obese)
▪ Eating diets that include fruits, vegetables, whole grains, and lean protein
▪ Limiting saturated and trans fats, added sugars, and highly or ultra-processed foods
▪ And others
Learn more in the article by Brian Chicoine, MD, linked below.
🔗https://adultdownsyndrome.org/resources/masld/