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Center for Complex Neurology, EDS & POTS

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Center for Complex Neurology, EDS & POTS

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The office of David Saperstein, MD. We specialize in EDS, POTS, Dysautonomia, Long Covid, CCI, Chiari Malformation, MCAS, and other autonomic disorders.

10/20/2026

Patients with MCAS (Mast Cell Activation Syndrome) may experience numerous symptoms, which can significantly disrupt daily life. This activation can impact several organ systems, including the respiratory, cardiovascular, skin, gastrointestinal, musculoskeletal, and nervous systems. The graphic provides examples of potential effects associated with different MCAS mediators.

Please note: This list is not comprehensive and serves only as an example. Mast cells secrete a range of mediators that lead to numerous symptoms across various organ systems.

MCAS can be hard to diagnose. There are blood and urine tests, but these are frequently normal. The symptoms of MCAS can often be brought under control through the use of antihistamines, mast cell stabilizers, and other medications.

Dr. David Saperstein worked with a group of mast cell activation specialists, led by Dr. Lawrence Afrin to propose new diagnostic criteria to update a Diagnosis Journal first published on January 22, 2014. This journal is called Diagnosis of Mast Cell Activation Syndrome: a Global “Consensus-2”.

Head to our website to learn more about MCAS now.

10/20/2026

💡Did you know that 91% of POTS patients report experiencing fatigue as a main symptom?!😴

🔎 POTS (Postural Orthostatic Tachycardia Syndrome) produces dizziness with standing and activity. It is a disorder of the autonomic nervous system (the autonomic nervous system controls functions that occur automatically like heart rate, blood pressure, digestion, and sweating). Other symptoms include fatigue, nausea, vomiting, headaches, and fainting.

Drop a 💙 in the comments if you can relate.

⁣

10/18/2026

✨ Long COVID is not always linear.➖

Symptoms can come and go, change over time, and affect people in very different ways, sometimes lasting months or even years. 📅

For some, this goes beyond discomfort and can impact daily function and quality of life.

♦ This is why awareness matters.
♦ This is why patients need to be taken seriously.

🔗 Learn more about Long COVID and what our Center has to offer.
📲 Check out Dr. Saperstein’s videos about Long Covid.
https://bit.ly/LONG-COVID

💬 Do you think Long COVID is still being misunderstood?🤔

10/16/2026

🔬✨ The Diagnosis of MCAS by Dr. David Saperstein

Mast Cell Activation Syndrome (MCAS) is a complex condition where your allergic system goes into overdrive, causing unpredictable reactions like rashes, hives, heightened skin sensitivities, and much more. It's especially common in patients with , , or .

💡 Diagnosing MCAS can be tricky. While blood and urine tests are available, they often come back normal. But with the right medications, including antihistamines and mast cell stabilizers, symptoms can be managed!

💥 Dr. Saperstein, alongside a team of experts including Dr. Lawrence Afrin, has helped update global diagnostic criteria for MCAS, improving the understanding of this challenging condition.

👉 If you or someone you know is dealing with MCAS or related symptoms, get in touch! Our team is here to help with personalized care. (Link in bio)

👉 If you or someone you know is dealing with MCAS or related symptoms, get in touch! Our team is here to help with personalized care. (Link in bio)

10/15/2026

💙 Dysautonomia After COVID 💙

Doctors are seeing more and more patients develop dysautonomia after recovering from COVID. For many, this looks like POTS-like symptoms; dizziness, rapid heart rate, and fatigue that can last months or even years.

This is real. This is happening. And it deserves awareness.

🔁 Share this to help others know they’re not alone.

💬 Have you or someone you know experienced new or worsening symptoms after COVID? If yes, drop a 🎗️ in the comments to raise awareness.

10/14/2026

🔥 Did you know?! Some POTS symptoms can be relieved simply by lying down! 🛏️⬇️ This helps restore normal blood flow to the brain and organs, making it easier to function.

POTS makes standing, moving, and even everyday activities a challenge due to improper blood flow. That’s why rest isn’t laziness, it’s necessary!

💬 Tell us in the comments if laying down helps you. 💙
🏷️ Share and repost to help raise awareness for Dysautonomia this month.

10/14/2026

🚨 Is Your Heart Racing for No Reason? It Could Be IST! 💙⚡️

Have you ever felt your heart pounding out of nowhere, even when you’re at rest? You might be dealing with Inappropriate Sinus Tachycardia (IST), a form of dysautonomia that affects around 1.2% of the population. 🫀💨

📌 Swipe through this post to learn:
✅ What IST is & how it affects the heart 💓
✅ IST prevalence 🌎
✅ Common symptoms (like dizziness, fatigue, and chest pain) 😵‍💫

Drop a 💙 in the comments if you or someone you know has IST, POTS, or Dysautonomia!

🔄 SAVE & SHARE this post to raise awareness for Dysautonomia this month.

📲 Follow Center for Complex Neurology, EDS & POTS to learn more about IST, POTS, and dysautonomia!

10/12/2026

💙 RATE YOUR DYSAUTONOMIA DAY💙

🎗️ October is Dysautonomia Awareness Month!
If you live with POTS or Dysautonomia… this one’s for you 👇

𝐑𝐀𝐓𝐄 𝐘𝐎𝐔𝐑 𝐃𝐀𝐘 𝐮𝐬𝐢𝐧𝐠 𝐭𝐡𝐞 𝐞𝐦𝐨𝐣𝐢 𝐬𝐜𝐚𝐥𝐞 𝐢𝐧 𝐨𝐮𝐫 𝐏𝐎𝐒𝐓💬

📣 Help spread the word:
💬 Drop your emoji in the comments
👥 Tag a friend to rate their day too
💾 Save this post so you can compare tomorrow
🔁 Share to help raise awareness this month

10/11/2026

✨ Dysautonomia doesn’t look the same for everyone.

🩺 For some, symptoms are mild and manageable. For others, they can be deeply disabling, impacting daily tasks, independence, and quality of life. And in rare cases, dysautonomia can become life-threatening.

Every patient’s experience is real, valid, and deserving of understanding and support.
Awareness is the first step toward better care, better research, and better outcomes for this community.

If you believe more people should understand the realities of dysautonomia, drop a 💙 in the comments or share 🔄 this post to spread awareness.

10/11/2026

🔎 When the autonomic nerves don’t function properly in Dysautonomia, the GI tract can be seriously affected. Symptoms may include:
🔹 Nausea
🔹 Vomiting
🔹 Constipation
🔹 Diarrhea
🔹 Abdominal Pain
🔹 Gastroparesis
🔹 Weight Loss
🔹 Malnutrition
🔹Weight Gain
🔹and MORE!

🩺 Dysautonomia is often invisible, misunderstood, and under-recognized. Having the right physicians matters. With over 25 years of experience, Dr. Saperstein specializes in diagnosing and managing Dysautonomia so patients can get real answers and real support.

💡 Were you surprised that Dysautonomia can affect the entire digestive system?

💬 Have YOU experienced any of these GI symptoms with Dysautonomia?

🔁 Share raise awareness about Dysautonomia.
📌 Save it to revisit or educate others later.
❤️ Like to help this reach more people.

Address

1010 E McDowell Road. , Suite 101
Phoenix, AZ
85006

Opening Hours

Monday	8am - 4pm
Tuesday	8am - 4pm
Thursday	8am - 4pm
Friday	8am - 4pm

Telephone

+16029009404

Website

http://www.complexneurology.com/

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