Synergy Performance and Rehabilitation

08/26/2026

Referred pain does not tell a clear “secret cause of your pain” story.

06/18/2026

This quote obviously resonates with a lot of people, but I am going to pull rank: it resonates with me MORE.

As an independent science journalist, that is.

Sometimes I feel like I am mostly earning a living from the customers I haven’t pi**ed off yet. 😜

I have been learning this the hard way for two decades now.

PainScience.com has always been about trying to make that sweet, adequate “living” by telling the truth to those who want the truth — and I am here to tell you, it’s a ridiculous business plan! Because two thirds of those people only THINK they want the truth. Or is it four fifths? Anyway, it’s too many, and they all LOOOOVE my work right up until I tip over one of THEIR sacred cows, and then suddenly they cannot cancel their memberships fast enough. Sad trombone.

I know it’s POSSIBLE to make a living this way because I’m still doing it somehow after all these years, and I have the best people in the world to thank for that. But those people are RARE — so hard to find that you can’t make a GOOD living this way, and most cannot manage it at all.

~ Paul Ingraham, PainScience.com publisher

05/12/2026

07/20/2025

The next frontier in medicine isn’t another drug.

It’s a radical shift in how we view the body, the brain, and disease itself.

Depression is often rooted in systemic inflammation, gut dysbiosis, mitochondrial dysfunction, insulin resistance, trauma, or disrupted circadian rhythms. ADHD may be tied to neuroinflammation, poor blood sugar control, or nutritional gaps like low magnesium, zinc, or omega-3s. And heart disease? It’s largely a food-borne illness, driven by a diet of ultra-processed, inflammatory, nutrient-poor calories.

There is no single root cause. But there are root causes.
And they are almost always connected by lifestyle, environment, and systems-level dysfunction.

Medications have their place… But they were never designed to reverse chronic disease. They manage symptoms, often while the underlying dysfunction worsens.

If we want to reverse the chronic disease epidemic, mental and physical, we need to stop asking what drug treats this and start asking why the body lost balance in the first place.

The answer isn’t in the pharmacy… It’s in how we eat, move, sleep, connect, and live.
It’s in our soil, our food system, our communities, our kitchens.

The next revolution in medicine will come not from the lab but from returning to the root.

07/15/2024