Manuel Astruc M.D.

06/09/2026

Sometimes growth is not a massive leap.

Sometimes it is just trying something a little different.

For me, that started with public speaking. I never expected how much I would enjoy it or how much it would enrich my life.

Small doors can lead to big changes.

06/03/2026

Burnout rarely happens all at once.
It builds quietly over time.
You lose energy.
You lose perspective.
You stop enjoying the life you worked so hard to build.
In 2008, a moment with my twin sister changed the way I viewed happiness, work, and success.
That moment started a very different journey for me.

06/03/2026

Grateful to have been part of yesterday’s panel at the Future Pharma conference in Boston discussing how AI, advocacy, and innovation are shaping the future of women’s wellness.

One theme that stood out throughout the conversation: technology can improve care, but it can’t replace human connection.

As healthcare continues to evolve, our challenge is making sure innovation helps people feel more seen, understood, and supported.

Thank you to Heidi Floyd, Mark Dente, MD, Alison Tapia, and everyone who contributed to such a thoughtful discussion.

05/11/2026

Running a family business is unlike anything else.
The pressure doesn't clock out at 5pm. The stakes are personal. And more often than not, your identity gets completely wrapped up in it.

Jason Packer lived this firsthand — as CEO of his family's business, he pushed hard, burned out, and eventually had to rediscover who he was outside of work after the business was sold.

Now he helps other family businesses avoid the same pitfalls through Stride, a community built for multigenerational family enterprises.

Our conversation on Happiness Rules is out now.

What happens when the family business becomes your whole identity — and then it's gone?Jason Packer grew up surrounded by family businesses. He eventually be...

05/04/2026

How much of what we’re experiencing right now is actually just an old pattern wearing a new face?

Karen Carey and I get into this and a lot more in this week’s episode of Happiness Rules. Now live on YouTube. Link in bio.

05/01/2026

You are not behind in your own life.

Read that again.

Karen Carey dropped two rules she lives by, and honestly, we needed to hear both of them.

Practice, not perfection.
You can't be behind in your own life.

It's your life. You haven't missed a deadline. You haven't fallen short of someone else's timeline. You have lived every single moment that brought you here.

Stop. Take a breath. You're exactly where you need to be.

New episode of Happiness Rules drops Monday.

04/20/2026

A lot of people stall out waiting to feel ready.

They research, prep, talk it through. Try to build up enough confidence to actually start. But Dan Sullivan’s framework flips that. Confidence is the fourth stage, not the first.

Commitment, then courage, then capability. Courage never feels good. That’s not a bug.

Full episode is live.

04/17/2026

For most people, work moves slowly. A rough quarter, a good one. Things ebb and flow over years.
Entrepreneurship doesn't work like that.
The same range of highs and lows gets squeezed into weeks. Sometimes days. Noa Simons described it as nervous system compression, and once she said it, it's hard to unsee.
Full episode drops Monday.

04/10/2026

We’re taught to be certain.
Have the answer.�Move fast.�Be right.
But what if that’s part of the problem?
“Be a little less certain. Be a little more curious.”
Full episode Monday.

04/06/2026

You can hit every goal you set…
and still feel like something’s missing.

In this episode, Jeff Oskin shares what changed his definition of success after years of building and scaling companies.

Why burnout happens even when things are “working”

What leaders overlook while chasing growth

And how stepping back changes everything

Full episode is live: https://youtu.be/J7bPlLU7HMA