Core Function Health - Michele Missakian, PA-C

Core Function Health - Michele Missakian, PA-C No medical advice
📞 Book a free 15min consult Not Medical Advice. Core Function Health is a California Physician Assistant Professional Corporation.

Hormone health | Thyroid | Metabolic wellness | Longevity medicine
✨Personalized, evidence-based care for women and men who refuse to just "age gracefully."
📍Serving California
📚 Educational content only. Core Function Health is a California Physician Assistant Professional Corporation providing evidence-based hormone optimization, thyroid health, metabolic wellness, weight management, and longevity-focused care for California residents. With nearly 20 years of clinical experience and further advanced training in hormone optimization, metabolic health, weight management, and functional medicine principles, Core Function Health takes a personalized approach to helping patients better understand the factors that influence how they feel, function, and age. Many individuals struggle with symptoms such as fatigue, weight gain, brain fog, poor sleep, low libido, mood changes, and declining vitality despite being told their laboratory results are "normal." Core Function Health was created to provide a more comprehensive, patient-centered approach that looks beyond symptoms alone and focuses on identifying contributing factors that may impact overall health and well-being. Services are designed to support hormone balance, thyroid function, metabolic health, healthy aging, and long-term wellness through individualized treatment plans, education, and ongoing support. Care can be delivered virtually to California residents, making expert guidance accessible from the comfort of your own home. At Core Function Health, the goal is simple: to help patients feel heard, supported, and empowered to optimize their health and quality of life.

🌿 Learn more and schedule a complimentary 15-minute consultation:
[www.corefunctionhealth.com](http://www.corefunctionhealth.com)

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IMPORTANT DISCLOSURES

🚫 Educational Content Only. The information shared on this page and through associated social media content is intended solely for educational and informational purposes and should not be considered medical advice, diagnosis, or treatment. Viewing, following, commenting on, messaging, or interacting with this page does not establish a patient-provider relationship. Clinical services are provided by a licensed California Physician Assistant pursuant to California law and under a formal written practice agreement with a licensed California physician. Some therapies discussed on this page may involve off-label use of FDA-approved medications. Certain compounded medications may not be reviewed or approved by the U.S. Food and Drug Administration (FDA). Treatment recommendations are individualized and based on a comprehensive medical evaluation, informed consent, and clinical judgment. Information presented on this page is not a substitute for medical care from your personal healthcare provider. Always consult a qualified healthcare professional regarding medical concerns and before making changes to medications, supplements, diet, or treatment plans. Services are available only to patients physically located in California at the time of their appointment.

09/19/2026

Your circle is part of your health. 🤍

Research has consistently linked strong social relationships with better health and longevity, while loneliness and social isolation have been associated with poorer health outcomes.

And connection isn’t about having a huge circle.

It’s about having the right people.

People who ask how you’re doing. Who are genuinely curious about your life. Who show up. Who celebrate your wins. And, just as importantly, people you want to show up for too.

Healthy relationships have reciprocity.

Sometimes protecting your energy doesn’t require an argument, an explanation, or cutting someone off. It simply means noticing where the effort is mutual, and investing more of yourself there.

Choose people who root for you. And be someone who roots for them right back. 🤍

📍 Core Function Health | Seal Beach, California
In-person + virtual care for California residents

Medical disclaimer: This content is for general educational purposes only and is not intended to diagnose, treat, or replace individualized medical advice from your healthcare provider.

09/18/2026

Do you have to stay on a GLP-1 medication forever?

The answer isn’t as simple as yes or no.

For some people, obesity is a chronic medical condition that may benefit from long-term treatment. Others may be able to gradually come off medication after building sustainable habits, preserving muscle, improving nutrition, and addressing the underlying factors contributing to weight gain.

The goal shouldn’t just be losing weight—it should be improving your long-term metabolic health and having a plan to maintain your results.

If you’re a California resident looking for individualized medical weight management, I’d love to help.

🌐 Book here: www.corefunctionhealth.com

Medical Disclaimer: This content is for educational purposes only and is not intended as medical advice. GLP-1 medications are prescription medications and may not be appropriate for everyone. Individual treatment decisions should be made with a qualified healthcare professional.

09/15/2026

Could your genes change the HRT conversation? 🧬🧠

APOE4 is the strongest common genetic risk factor for late-onset Alzheimer’s disease, but carrying APOE4 does NOT mean you will develop Alzheimer’s.

Here’s where it gets interesting: researchers are studying how APOE status, declining estrogen during menopause, and the timing of menopausal hormone therapy may intersect with brain health.

Some studies have found associations between HRT use and favorable cognitive or brain-volume outcomes in women carrying APOE4. Newer research, including recent Stanford research examining estrogen-based menopausal hormone therapy and Alzheimer’s-related brain changes, is adding another piece to the puzzle.

But there’s an important caveat:

HRT is NOT currently recommended solely to prevent or treat Alzheimer’s disease, and the research is not conclusive. Genetics, timing of therapy, hormone formulation, cardiovascular and metabolic health, and individual medical history all matter.

Your genes may influence risk. They don’t determine your future, and they shouldn’t be interpreted in isolation.

I broke down the research on APOE4, estrogen, menopause, HRT, and Alzheimer’s risk in my newest blog.

🔗 Read the full article at Core Function Health — link in bio.

📍 Based in Seal Beach, serving Los Alamitos, Rossmoor, Long Beach, Cypress, Huntington Beach, Orange County, Los Angeles, and patients throughout California.

⚕️ Educational content only. This information is not medical advice and is not intended to diagnose, treat, cure, or prevent any disease. Hormone therapy has individualized benefits, risks, and contraindications and should be discussed with a qualified healthcare professional.

You swiped, didn’t you? 👀😂Here’s the thing: p3ptides aren’t inherently “good” or “bad,” but they also aren’t something I...
09/14/2026

You swiped, didn’t you? 👀😂

Here’s the thing: p3ptides aren’t inherently “good” or “bad,” but they also aren’t something I believe should be DIY’d based on a TikTok, Reddit thread, or a vial purchased from a research website.

I DO offer p3ptide therapy in my practice when clinically appropriate.

But before recommending anything, I look at the whole picture: your medical history, current medications, goals, baseline labs, potential risks, and whether a particular therapy actually makes sense for YOU.

And if we decide a p3ptide is appropriate, it’s prescribed as part of an individualized treatment plan with ongoing medical oversight, not “here’s a vial, good luck.” 😉

There’s a big difference between having access to something and knowing whether it’s appropriate for your body.

📍 Core Function Health | Seal Beach, California
In-person visits in Seal Beach + virtual care throughout California.

✨ Want to learn whether one of my programs may be appropriate for you? Book a complimentary discovery call through the link in my bio.

⚕️ Medical disclaimer: This content is for general educational and informational purposes only and is not medical advice. It does not establish a patient-provider relationship. Individual risks, benefits, contraindications, and treatment options should be discussed with a qualified healthcare professional. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality before marketing.

09/09/2026

Come out for some family fun! 🤍

I’m excited to be one of the sponsors of this event and to spend the day with our local community.

Stop by the Core Function Health booth, say hi, and learn a little more about me and what I do. Whether you’re curious about hormones, metabolic health, medical weight management, longevity, or just want to meet the person behind all the posts, come find me! 😊

Bring the family, enjoy the event, and make sure you stop by and say hello. I’d love to see you there!

📍 In-person in Seal Beach + virtual throughout California
🌐 corefunctionhealth.com

🎥 Video credit: Family Foodie Festivals

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909 Electric Avenue , Suite 312C
Seal Beach, CA
90740

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Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

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