Colibris Canna Consulting & Coaching

09/10/2026

https://www.science.org/doi/10.1126/science.aec6116?fbclid=IwZnRzaAUQEtVwZG9mBWZkaWQWUOLAWRcc9G2-1DoOaE-1zTBuFQBk9GV4dG4DYWVtAjExAHNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7oJf5M50oNd2LF88VjQdI7aBazz2hOJ2Heuo-45ZbmlCXyyG0zwozRrGZcCQ_aem_w6Qhs4NAJFnZHpFUZjzmnw

Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this work, we show that as little as two doses of ...

05/20/2025

Recent advances in cancer research have unveiled innovative strategies that cause cancer cells to destroy themselves. At Penn State University, scientists have developed a modular genetic circuit that turns cancer cells into “Trojan horses,” reprogramming them to initiate their own death while also eliminating surrounding drug-resistant cells. This technique has delivered promising results in lab-grown human cells and mouse models, offering a potential breakthrough in tackling cancer’s complexity and resistance to standard treatments.

Meanwhile, another team of researchers has designed a cutting-edge molecule to fight blood cancer by targeting the BCL6 protein—a key player in helping cancer cells evade death. By linking BCL6 with the BRD4 protein, this new compound reactivates suppressed cell death signals, triggering the cancer cells to self-destruct. This development introduces a powerful new class of cancer therapies with broad potential across various types of cancer.

02/19/2025

https://pmc.ncbi.nlm.nih.gov/articles/PMC4960344/?fbclid=IwZXh0bgNhZW0CMTEAAR1UHfixxrrf4uIuArRzqhFjuHbZSzEajV3vSJ6J36aRyGA8OzmRItauEh0_aem_zuSWUjcQVBvPNaK5_bBEGw

01/27/2025

Low-doses of THC, CBD, & CBG. . .

A study by the University of the Basque Country (UPV/EHU) demonstrates that the drug WIN55,212-2 protects the brain and reverses early cognitive damage caused by dementia, while also explaining its mechanism of action. Over two decades of research conducted by the Neurochemistry and Neurodegenera

01/14/2025

10/29/2024

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10/10/2024

. . . this is a real problem … 22 Vets a day surrender to their demons. May I please get 2 friends or family members (out of all my friends on my page) to copy & re-post? Someone’s life may depend on it.
call: 988

10/06/2024

We already knew this and that full-spectrum tends to work better, but these results are encouraging nonetheless in my opinion: "Results from the dronabinol group show . . . a 30% decrease compared to the scores in the placebo group which did not change. Additionally, dronabinol was well tolerated by patients compared to current treatments for agitation. 'Results like this are encouraging. We are thrilled that FDA-approved dronabinol was robustly effective and appeared safe for treatment of agitation,' says Rosenberg. 'This adds another tool in our efforts to improve the care of our loved ones with Alzheimer’s disease.'”

Patients tolerated synthetic THC (dronabinol) well, without the adverse effects commonly associated with existing Alzheimer's agitation medications. A study conducted by researchers from Johns Hopkins University School of Medicine and Tufts University School of Medicine found that a pill form of dr

09/19/2024

"Tumour mutational burden (TMB): Tumours with a high number of mutations tend to produce more neoantigens, making it easier for the immune system to recognize and attack them. TMB has been one of the most studied biomarkers for predicting response to CPIs.

Effective T-cell infiltration: The presence of cytotoxic T-cells in the tumor is essential for the effectiveness of CPIs. This study has confirmed that a higher infiltration of these cells is directly related to a better response to the therapy.

TGF-β activity in the tumor microenvironment: This factor influences the behavior of some cells in the tumor microenvironment. High TGF-β activity can suppress the immune response, which is reflected in a tendency for patients to have poorer survival after immunotherapy treatment.

Previous treatment: Patients who have received previous treatments tend to show a poorer response to immunotherapy.

Tumour proliferative potential: Patients with tumors that have a high proliferative index, which tends to be more aggressive, generally show poorer survival after treatment."

Researchers identified five factors that predict response to immunotherapy, advancing personalized cancer treatment. This could help target therapy more effectively, reducing unnecessary side effects. Immunotherapy has revolutionized cancer treatment by harnessing the immune system to target tumo

08/26/2024

"Scientists have discovered a protein that can directly halt DNA damage. Better yet, a new study shows it appears to be 'plug and play', theoretically able to slot into any organism, making it a promising candidate for a cancer vaccine."

Abstract. The bacterium Deinococcus radiodurans is known to survive high doses of DNA damaging agents. This resistance is the result of robust antioxidant