08/13/2026
YOU NEED TO ORDER THIS LAB: HOMOCYSTEINE
Homocysteine is a simple blood test that can give us valuable information about methylation and one-carbon metabolism, yet it isn't always included in routine blood work.
Why might I order it?
• Evaluate methylation function
• Identify possible B12, folate, B6, or B2 insufficiency
• Assess cardiovascular risk
• Investigate fatigue or brain fog
• Evaluate cognitive or neurologic concerns
• Determine whether an MTHFR variant may be functionally significant
A genetic variant like MTHFR tells us what could happen. Homocysteine can help us understand what is actually happening.
If homocysteine is elevated, the next question is always: Why?