WashU Medicine Knight ADRC

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The Washington University Knight ADRC is one of around 30 centers funded or otherwise supported by the National Institute on Aging with the collective aim of facilitating advanced research on Alzheimer Disease.

New Brain Scan Could Spot Alzheimer’s Earlier Than Current Tests
06/01/2026

New Brain Scan Could Spot Alzheimer’s Earlier Than Current Tests

Advanced brain imaging using a next-generation tau tracer revealed more Alzheimer’s-related pathology than current methods, supporting earlier diagnosis and more precise disease staging.

Scientists found the hidden switch fueling alzheimer’s brain inflammation
06/01/2026

Scientists found the hidden switch fueling alzheimer’s brain inflammation

Scientists at Scripps Research have uncovered a molecular “switch” that appears to fuel the damaging brain inflammation seen in Alzheimer’s disease. They found that a protein called STING becomes chemically altered in a way that keeps the brain’s immune system stuck in overdrive, harming the...

Alzheimer's disease neuropathology plasma biomarkers and cognition in midlife: a community-based cohort study
05/30/2026

Alzheimer's disease neuropathology plasma biomarkers and cognition in midlife: a community-based cohort study

Alzheimer's disease neuropathology is relatively uncommon in midlife but associated with worse cognitive performance and accelerated decline and might have stronger association among some groups. Early Alzheimer's disease neuropathology detection with the use of plasma biomarkers might enable timely...

Detecting Alzheimer’s Early by Brain Scan or Blood
05/29/2026

Detecting Alzheimer’s Early by Brain Scan or Blood

Identifying early signs of Alzheimer’s may allow individuals time to address potential risk factors in their lives.

St. Louis researchers receive recognition for groundbreaking Alzheimer’s diagnostic test
05/29/2026

St. Louis researchers receive recognition for groundbreaking Alzheimer’s diagnostic test

A blood test developed by the founders of C2N Diagnostics was the first of its kind to measure a key marker of Alzheimer's disease in patients.

New brain scan detects Alzheimer’s tau earlier than current standard
05/29/2026

New brain scan detects Alzheimer’s tau earlier than current standard

In one of the largest head-to-head tau PET comparisons conducted to date, PET tracer MK6240 identified 23 additional tau-positive cases per 100 scans in cognitively healthy people with amyloid pathology, compared to Flortaucipir.

An unexpected molecular explanation for how tau aggregation begins in Alzheimer’s disease
05/29/2026

An unexpected molecular explanation for how tau aggregation begins in Alzheimer’s disease

Disruption of a neuronal-specific protein degradation system, the plasma membrane-bound neuroproteasome, triggers the conversion of endogenous tau into aggregates that mirror those seen in patients with Alzheimer’s disease (AD). Aging and APOE4 — the largest risk factors for AD — induce neurop...

A Liver Enzyme Produced During Exercise Might Reverse Memory Loss
05/29/2026

A Liver Enzyme Produced During Exercise Might Reverse Memory Loss

A Liver Enzyme Produced During Exercise Might Reverse Memory Loss on Simons Foundation

New Study Finds Clues of Alzheimer’s Beginnings
05/29/2026

New Study Finds Clues of Alzheimer’s Beginnings

A new Columbia study shows how tau filaments—protein clumps that are closely linked to memory decline in Alzheimer’s—get their start, raising the prospect of stopping their production at its source.

Bateman and Holtzman receive 2026 American Innovator Award
05/29/2026

Bateman and Holtzman receive 2026 American Innovator Award

WashU Medicine researchers Randall J. Bateman, MD, and David M. Holtzman, MD, were honored for their work developing diagnostic blood tests for Alzheimer's disease with the Bayh-Dole Coalition’s 2026 American Innovator Award.

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4488 Forest Park, Suite 101
St. Louis, MO
63108

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Thursday 8:30am - 4:30pm
Friday 8:30am - 4:30pm

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+13142862683

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