10/20/2026
Pregnancy is hard work for the heart. For most women, the heart handles the strain just fine. But for some, the heart muscle suddenly becomes weak around the time of childbirth, leading to a condition known as peripartum cardiomyopathy (PPCM).
Affecting roughly 1 in every 2,200 births in the US, PPCM can be life-threatening, and currently, there is no medicine made specifically to treat it.
At The Lundquist Institute, Investigator Michelle L. Matter, PhD, and her team are searching for answers in our genes. Through the PERCVD Trial, in partnership with Woman’s Hospital in Baton Rouge, Louisiana, researchers are studying genetic changes that might explain why some women's hearts struggle during pregnancy.
Discover how Dr. Matter's research could help more mothers stay healthy: https://lundquist.org/news/when-pregnancy-strains-the-heart-searching-our-dna-for-answers-on-heart-failure/