08/05/2026
Not all cases of primary aldosteronism are the same,and neither are the outcomes after surgery.
A modern pathology classification called HISTALDO is changing the way specialists evaluate adrenal tumors that cause primary aldosteronism (Conn syndrome). Unlike traditional pathology, which only examines the appearance of adrenal tissue, HISTALDO identifies the cells actively producing excess aldosterone, providing a clearer understanding of the disease driving a patient's high blood pressure.
This advanced approach helps physicians better predict how much blood pressure is likely to improve after surgery, whether potassium levels will normalize, the likelihood of reducing or eliminating blood pressure medications, and which patients may benefit from more personalized long-term follow-up.
At the Carling Adrenal Center, HISTALDO classification is routinely performed for every patient undergoing adrenalectomy for primary aldosteronism, ensuring treatment decisions and postoperative care are guided by the most advanced pathology available.
Read the full article here: https://www.adrenal.com/blog/histaldo-classification-in-primary-aldosteronism-what-every-patient-needs-to-know