17/09/2026
THE RELATIONSHIP BETWEEN AUTISM, ADHD, ANXIETY, DEPRESSION AND GENETICS
A new peer-reviewed study investigated whether ADHD, anxiety, depression and other conditions occurring alongside autism are linked to the same genetic influences as autism or involve additional genetic factors.
Researchers analysed diagnostic information from 74,204 autistic participants. Genetic analyses included 17,582 participants, while within-family analyses included 5,236 parent-child trios.
The diagnoses formed three broad clusters:
• ADHD and disruptive behaviour disorders
• Depression and anxiety
• Schizophrenia and bipolar disorder
The researchers found evidence that these clusters had additional genetic influences rather than simply reflecting the genetic influences associated with autism itself.
In practical terms, ADHD, anxiety and depression should not automatically be viewed as symptoms or expressions of autism.
Autism and ADHD are separate conditions, although they can occur together. Having autism does not automatically mean someone has ADHD, and having ADHD does not automatically mean someone is autistic.
This is why Spectrum Centre assesses autism and ADHD separately. Each condition has its own DSM-5 diagnostic criteria and requires its own careful clinical assessment. Where both are assessed, we use separate sessions and provide separate reports.
The study does not mean that genetics alone causes these conditions. Mental health and functioning are also shaped by relationships, stress, trauma, discrimination, environmental demands and access to appropriate support.
It also highlights why diagnosis is only the beginning.
A diagnosis may provide clarity, but people may still need support with anxiety, depression, burnout, executive functioning, relationships, identity, masking, emotional regulation and the practical demands of everyday life.
This is why we encourage clients to consider ongoing therapy after diagnosis.
Long-term therapy is not about treating autism or ADHD or making someone appear less neurodivergent. It provides time to understand how each different conditions, experiences and environments interact in that individual person’s life.
We are all unique.
Source: Okewole et al., Molecular Psychiatry, published 12 September 2026.
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