20/07/2023
Researchers have made a groundbreaking discovery about metabolic health and aging! 🌟
A study in 2021 investigated the effects of Nicotinamide Mononucleotide (NMN) supplementation on postmenopausal women with prediabetes who were overweight or obese. 🌺
NMN is crucial for the biosynthesis of NAD+, an essential molecule for metabolic function. Previous studies in rodents showed that obesity and aging impair NAD+ biosynthesis, leading to metabolic dysfunction. 🐭
In this 10-week, randomized, placebo-controlled, double-blind trial, the results were incredible! The group receiving NMN supplementation experienced:
✅ Improved insulin-stimulated glucose disposal
✅ Increased skeletal muscle insulin signalling (phosphorylation of AKT and mTOR)
✅ Up-regulation of genes related to muscle remodelling, including platelet-derived growth factor receptor β
These findings suggest that NMN supplementation may enhance muscle insulin sensitivity, insulin signalling, and muscle remodelling in postmenopausal women with prediabetes who are overweight or obese. 💪
This study opens up exciting possibilities for addressing metabolic dysfunction in this specific population. 🌈 Let's stay tuned for further developments in this exciting area of research! 🤩
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