07/13/2026
Many people are surprised to learn that certain nutrients continue to be studied for their potential relationship with preeclampsia risk.
For Example:
Calcium
Vitamin D
Folic acid
These have all been explored in the research, with studies suggesting possible associations between nutritional status and pregnancy outcomes.
What these findings remind us is that pregnancy health is nuanced. The goal is not to self-prescribe supplements or chase individual nutrients, but to understand your own needs with the support of a qualified healthcare professional.
Personalized care can help you make informed choices that fit your health history, risk factors, and stage of pregnancy.
References:
Hofmeyr, G. J., Lawrie, T. A., Atallah, Á. N. & Torloni, M. R. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database Syst. Rev.2018, CD001059 (2018).
Kinshella, M. W. et al. Calcium for pre‐eclampsia prevention: A systematic review and network meta‐analysis to guide personalised antenatal care. BJOG: Int. J. Obstet. Gynaecol.129, 1833–1843 (2022).
O’Callaghan, K. M. & Kiely, M. Systematic Review of Vitamin D and Hypertensive Disorders of Pregnancy. Nutrients10, 294 (2018).
Purswani, J. M. et al. The role of vitamin D in pre-eclampsia: a systematic review. BMC Pregnancy Childbirth17, 231 (2017).
AlSubai, A. et al. Vitamin D and preeclampsia: A systematic review and meta-analysis. SAGE Open Med.11, 20503121231212093 (2023).
Rouhani, P., Mokhtari, E., Lotfi, K. & Saneei, P. The association between circulating 25-hydroxyvitamin D levels and preeclampsia: a systematic review and dose-response meta-analysis of epidemiologic studies with GRADE assessment. Nutr. Rev.81, 1267–1289 (2023).
Hu, K.-L., Zhang, C.-X., Chen, P., Zhang, D. & Hunt, S. Vitamin D Levels in Early and Middle Pregnancy and Preeclampsia, a Systematic Review and Meta-Analysis. Nutrients14, 999 (2022).