Dr_Jamie_Murphy

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Dr_Jamie_Murphy Specalist cancer surgeon in London with clinical & research interest in advanced colorectal and peritoneal cancers

Great summary of options before for Slide 1 are data for mismatch repair deficient cancers ( the c. 5-15% patients...
29/09/2026

Great summary of options before for Slide 1 are data for mismatch repair deficient cancers ( the c. 5-15% patients who are currently offered immunotherapy) with on left on right. Slide 2 are data for those who not currently candidates for immunotherapy (c. 85-95% cases). Slide 3 reminding us that complications of this treatment can be very significant and difficult to treat. Nevertheless very impressive data

Fantastic talk American College of Surgeons meeting explaining liquid biopsies, the difference between tumour informed...
28/09/2026

Fantastic talk American College of Surgeons meeting explaining liquid biopsies, the difference between tumour informed / tumour agnostic tests, emerging liquid biopsy technologies and how they can be used.

Fantastic session at American College of Surgeons covering acute care for patients receiving . While the focus was ...
27/09/2026

Fantastic session at American College of Surgeons covering acute care for patients receiving . While the focus was on emergency surgery the complexity and range of chemotherapy agents is now such that there are a lot of lessons for timing of surgery after chemotherapy for patients with . Highlights are in the pictures

Humbled and honoured to be elected as the Secretary General (Executive Director) Designate of the International Society ...
22/04/2026

Humbled and honoured to be elected as the Secretary General (Executive Director) Designate of the International Society of Surgery (ISS/SIC) the oldest international surgical society in the world at . ISS has included in its ranks surgical luminaries such as Prof De Quervain and Prof Theodor Kocher, the first surgeon to win the Nobel Prize. I look forward to working with my very close friends over the next two years - the incoming President Prof Alessandro Fichera, Dr Avital Harari, MD, MBA, MSc, FACS the incoming treasurer and mentorship and guidance from Prof Ken Boffard a legend in trauma surgery who I look forward to closely working with !

starts in 30 mins !
20/04/2026

starts in 30 mins !

🆕✨ Good news at the end of the year for people with advanced bowel cancer 🧬💙Thousands more patients in England and Wales...
31/12/2025

🆕✨ Good news at the end of the year for people with advanced bowel cancer 🧬💙

Thousands more patients in England and Wales 🇬🇧 will now be able to access an important cancer treatment on the NHS 🏥🤍

NICE ✅ has approved bevacizumab, a targeted cancer drug 💉🎯, to be used alongside chemotherapy for advanced (stage 4) bowel cancer. This decision was possible because lower-cost biosimilar versions 💊💷 are now available, making it affordable for the NHS 💙👏

So what does this mean? 👇
➡️ Bevacizumab helps slow tumour growth 🛑🧫
➡️ When added to chemotherapy, it can help people live longer before the cancer worsens ⏳📈
➡️ It offers another option when immunotherapy or other targeted treatments aren’t suitable 🔬❌

Around 7,000 more people 👥 are expected to benefit from this change 🌟

This is a great example of how advances in cancer treatment 🧠🔬 — and smarter use of NHS resources 💷🤝 — can translate into real benefits for patients 💙🙌

If you or someone you know has bowel cancer, always discuss treatment options with your cancer team 🗣️👩‍⚕️👨‍⚕️

🎗️ 💙 💉 🏥 🔬 CancerAwareness 📢 MedicalNews 📰 HopeInCancer ✨

🧬💉 Can a simple blood test help guide cancer treatment?New research shows that ctDNA testing after surgery 🏥 for stage...
20/12/2025

🧬💉 Can a simple blood test help guide cancer treatment?

New research shows that ctDNA testing after surgery 🏥 for stage 3 (involved lymph nodes) may help identify who benefits from adding celecoxib 💊 (a non steroidal anti inflammatory drug used as pain killer) to chemotherapy — with up to a ⬇️ 40% reduction in cancer recurrence and death 📉 for patients who are ctDNA-positive after surgery.

This is precision medicine in action 🎯 — moving away from one-size-fits-all care and toward smarter, personalized treatment 🧠✨.

Not every patient benefits ❌ — but the right patient might ✅.

👉 Save 💾 if you follow cancer research
👉 Share 🔁 to spread awareness
💬 Comment 💭: Should ctDNA testing become standard after surgery?

🆕 hope for advanced bowel cancer ✨The recently published STELLAR-303 trial has brought some 🌟 encouraging news 🌟 for peo...
21/10/2025

🆕 hope for advanced bowel cancer ✨

The recently published STELLAR-303 trial has brought some 🌟 encouraging news 🌟 for people living with stage 4 (advanced) colorectal cancer.

This large international 📖 tested a 🆕 treatment combo — 🧬 Zanzalintinib (tyrosine kinase inhibitor) + Atezolizumab (immunotherapy) — against the standard drug 💊 Regorafenib, which is approved for use in 🇬🇧 NHS and is usually used when first, second and third line treatments have stopped working. It’s important to highlight that the patients included in this study would not normally be candidates for immunotherapy (pMMR, MSS). A total of 901 patients were recruited and randomly allocated to the 🆕 or standard treatment options.

💡 What did it find?
➡️ People given the 🆕 combination had a longer average overall survival than people receiving Regorafenib — 10.9 months vs 9.4 months.
➡️ Interestingly the benefit from the new treatment was considerably greater for patients without spread to the liver — 15·9 months vs 12·7 months.
➡️ Side-effects were similar to other treatments (😴 tiredness, 💨 diarrhoea, 💓 high blood pressure) but were manageable with 👍 medical support.

🔬 Why it matters:
This combination brings immunotherapy and targeted therapy together for the majority of patients (micro satellite stable) — showing real hope for patients who’ve already had several rounds of treatment. It’s another step towards giving people more and better options.

💙 If you’re living with stage 4 bowel cancer, this doesn’t change today’s standard treatment just yet — but it’s a sign of hope that this new therapy may be available in the future. Talk to your oncologist to see if similar clinical trials might be open near you.

🌍💪💙

Great to see importance of young patients with being discussed at
06/10/2025

Great to see importance of young patients with being discussed at

Great honour to have been elected as Fellow of American College of Surgeons in Chicago today
05/10/2025

Great honour to have been elected as Fellow of American College of Surgeons in Chicago today

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