10/08/2026
If you are managing high blood pressure and doing everything correctly, yet the numbers barely move, it may be worth asking a different question.
Most people who reach me have already done the sensible things. The medication, the lower salt, the cardio. And still, the readings sit there, quietly stubborn. What tends to get missed is not effort. It is terrain.
Blood pressure is not only a salt-and-stress story. When the lining of your blood vessels, the endothelium, is exposed to steady, low-grade inflammation, it produces less nitric oxide, the compound that keeps arteries relaxed and open. With less of it, vessels stiffen, blood meets more resistance, and the heart works harder. In time, that shows up as a number.
So the useful question becomes - where might the inflammation be coming from. For some people, part of the answer sits in how their body handles gluten. If you carry a genetic predisposition to gluten-related immune reactivity, each exposure may prompt a low, persistent inflammatory signal, often without any obvious gut symptoms.
In 2024, researchers confirmed this pathway. They found (in mice) that gluten directly triggered increased blood pressure, impaired vascular relaxation, and inflammatory activity in heart and arterial tissue. The part that stopped me - when gluten was removed, the cardiovascular damage reversed.
Not managed, Reversed!
If you've been managing high blood pressure and nobody has ever mentioned your gut, your genes, or gluten, you haven't found the root cause yet.
That is what a functional DNA test is designed to map - how your body handles gluten, inflammation, methylation and detoxification, so that any change you make is matched to you rather than to a general rule.
If you would like to see what your own DNA suggests about how you handle gluten and inflammation, that is the place to start. Details are in the first comment.