27/07/2026
IBS, eczema, hayfever and migraine: four separate conditions — or could there be a common inflammatory link? 👀
When we looked more closely at data from our 440-patient RELIEVE IBS-D clinical trial, we found something unexpected.
📊 Among participants who also had eczema, hayfever, allergic rhinitis, migraine or food intolerance:
52.5% responded to Enterosgel® for their IBS-D symptoms
compared with
28.1% receiving placebo.
In the overall trial population, the responder rates were 37.4% with Enterosgel versus 24.3% with placebo.
Why might people with allergic or atopic conditions have responded more strongly?
🧬 One possible connection is the mast cell—an immune cell found in the gut, skin and around sensory nerves. When activated, mast cells release histamine and inflammatory mediators, including TNF-α and IL-1β.
🔬 In 2025, award-winning student research from Imperial College London found that Enterosgel adsorbed TNF-α and IL-1β in laboratory testing—adding an important piece to the scientific hypothesis.
This does not prove that Enterosgel treats eczema, hayfever or migraine. The subgroup finding was exploratory, and Enterosgel is indicated for IBS with diarrhoea and acute diarrhoea. But the signal is scientifically interesting—and deserves further research.
👉 Swipe through the carousel to see what we discovered.
📖 Read the full story through the link in our bio, or visit:
enteromed.co.uk/blogs/news
💬 Do your gut, skin, allergy or migraine symptoms ever flare at the same time? Comment GUT–SKIN below or DM us with your experience.
👩⚕️ Doctors, dermatologists, allergists and researchers interested in the gut–skin axis: DM us RESEARCH. We would genuinely like to hear from you.
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