03/08/2026
As the the meeting approaches, and with it our now-regular course on corneal perforations, I wanted to share this interesting case to highlight the importance of creative thinking when managing perforations in challenging clinical backgrounds.
This patient was suffering from peripheral ulcerative keratitis ( ) in the context of pyoderma gangrenosum. Despite immunosuppression, the disease had caused diffuse conjunctivalisation of the cornea and a corneal perforation. Despite repeated attempts at gluing and applying amniotic membrane to seal it, it continued to leak. The patient was keen to avoid evisceration, despite the limited visual prognosis. With this mini-DSEK, I managed to seal the perforation and restore the integrity of the globe, without disrupting the ocular surface, which could have led to further melting.
Full video on my YouTube channel https://youtu.be/WGxay9ox4Vs?is=APQTCdnX-x3_OhW_
.vasquez.perez