10/28/2026
Creatine has a strong track record for performance in specific types of exercise. Recently, researchers have been studying possible effects on cognition, sleep deprivation, and cardiometabolic markers.
For women in perimenopause and menopause, potential effects on muscle health and bone density are especially interesting.
If you take creatine, let your clinician know before kidney-function testing. Creatine can raise serum creatinine and affect estimates of kidney function.
The study referenced on slide 5 was published in the Journal of the International Society of Sports Nutrition on August 21, 2026.
The small study in perimenopausal and menopausal women tested creatine HCl alone and in combination with creatine ethyl ester; it did not test creatine monohydrate.