A Major Difference, Inc.

A Major Difference, Inc. A Major Difference is the manufacturer and worldwide distributor of the IonCleanse® ionic foot bath.
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Major Difference provides IonCleanse products in Centennial, CO

09/16/2026

Dr. Debbie Norman walks us through why binders (typically used in other forms of heavy metal detox) aren’t necessary when you’re using the IonCleanse by AMD.

With other forms of detox, you’re often introducing something into the system (through a pill or IV). In cases like this, binders are often paired with the detox therapy.

But with the IonCleanse by AMD, we don’t add anything else to the body. Instead, the ions and biocompatible current helps encourage the parasympathetic state in the user, leading to the body being able to detox at an accelerated rate.

This is why it’s so many wellness practitioner’s first choice when it comes to gentle (yet POWERFUL) detox.

One of our favorite things to hear from our community is that detoxing with the IonCleanse helped them need less of thei...
09/14/2026

One of our favorite things to hear from our community is that detoxing with the IonCleanse helped them need less of their expensive supplements. When the body’s detox pathways clear up, a lot of things tend to fall into alignment.

And while we believe detox is a lifelong initiative, we also know that it’s possible to one day enter a maintenance mode. (Where you detox less frequently to maintain the same results)

Curious about this? Send us a message to start the conversation. We’d love to answer your questions.

09/10/2026

Ever wonder why you feel so refreshed after a walk by the ocean or a waterfall?

There's actual science behind it. When moving water crashes against a surface, the impact splits water molecules apart and releases negative ions into the air. Researchers call this the Lenard effect, and it's why the air near waterfalls, shorelines, and dense forests feels noticeably different.

The numbers back it up. Studies measuring air near forests and waterfalls have recorded negative ion concentrations in the range of 2,000 to 5,000 ions per cubic centimeter. Indoor air in urban environments typically measures a small fraction of that.

The IonCleanse by AMD works with the same principle, using water, salt, and a gentle electrical current to generate ions in the footbath.

The filtered current delivered by the IonCleanse helps your body enter the parasympathetic state, also known as rest and digest. This is the state where your body does its restorative work. As you relax during a session, the ions in the water go to work.

We take pride in being nature-inspired and cutting-edge at the same time. Thirty minutes with your feet in the water, bringing a little of what makes those places feel so good into your own home.

Try it today and put our 60-day money-back guarantee to the test.

Do you feel like you need permission to relax? That it’s something you earn after a long day of work?Let us offer a diff...
09/10/2026

Do you feel like you need permission to relax? That it’s something you earn after a long day of work?

Let us offer a different way to think about it.

Relaxation isn’t laziness. Instead, think of it as your baseline.

Did you know that the body actually needs relaxation? Around here, we like to call it the “parasympathetic response,” but it is commonly called “rest and digest.” Your body’s repair systems work a lot better when you are relaxed.

The IonCleanse helps the body detox better because it encourages this parasympathetic state in the body. It’s a great way to help the body combat stress or a high toxic burden.

We don’t believe in earning rest around here. We see it as an essential part of being human.

So consider taking a moment for yourself today. Thirty minutes, warm water, feet in. Relaxation can’t be forced. But it can be cultivated.

09/04/2026

The color change gets a lot of attention.

And for good reason! As users can and do detox into the tub.

But one thing going on that isn’t as visible is the stimulation of the parasympathetic response in the body, also known as “rest and digest.”

This nervous system state is where repair happens in the body, and that includes necessary mechanisms like detox.

So not only do you detox into the IonCleanse tub, but you will also continue to detox at an accelerated rate for up to five days *after* your session.

This is why we often refer to the filtered current introduced by our medical grade power supply as the “secret ingredient.” No, it’s not a secret. But it doesn’t seem to get as much attention as the color change, even if it’s a big part of the benefit to this technology.

Skepticism doesn’t scare us. In fact, all of your questions are welcome here. A lot of our biggest believers started out...
08/31/2026

Skepticism doesn’t scare us. In fact, all of your questions are welcome here. A lot of our biggest believers started out as skeptics, so you are in good company.

What do you want to know about detoxing with the IonCleanse? Let us set the record straight.

08/27/2026

The Pay-Per-Cleanse program is a rent-to-own program. Once the user has paid off their machine, the rental unit will be shipped back to us, and they will receive a brand new IonCleanse. It’s a great way to get a device into your home with lower upfront costs. Here, Charles Zeitler runs us through the pro’s and con’s of our PPC program.

Interested in doing the PPC program? Comment below, and we’ll send you a link to sign up.

We don’t want to feel tired. We don’t want to feel pain. We don’t want to feel less than our best. It’s natural and oh-s...
08/25/2026

We don’t want to feel tired. We don’t want to feel pain. We don’t want to feel less than our best.

It’s natural and oh-so-human to want to feel only the good feelings.

But fatigue, pain, irritation, anxiety… these are all messages from the body, too. They aren’t necessarily ‘bad,’ even though they can cause incredible discomfort.

The more we can tune in to what our body is telling us, the less it will have to scream. What is your body asking for today?

08/24/2026

Detoxing the planet two feet at a time since 2002. 👣 The IonCleanse by AMD is a strong and yet gentle full-body detox that works by ionizing the water, splitting it into negative and positive ions.

There are more fun facts where these came from! What questions do you have for us?

If you’ve placed an order with us in the last two years, there’s a strong chance you have points waiting to be used on y...
08/19/2026

If you’ve placed an order with us in the last two years, there’s a strong chance you have points waiting to be used on your account! Here are all of the details about our rewards program so your points don’t go to waste.

Address

7318 S Revere Pkwy #B7
Centennial, CO
80112

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

Telephone

+13037550112

Website

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