10/22/2026
Today is Phelan-McDermid syndrome Awareness Day!
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What is Phelan-McDermid syndrome?
Phelan-McDermid syndrome is a rare genetic disorder involving chromosome 22. It can be caused by a deletion in region 22q13 or by a change (variant) in the SHANK3 gene.
It can affect communication, learning, movement, sleep, behavior, and many other areas of health and development. But Phelan-McDermid syndrome does not look the same for everyone. Each person has their own combination of strengths, challenges, needs, interests, and personality.
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Every question builds understanding. Every share helps awareness reach someone new.
Learn more at pmsf.org/pmsad.
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