Los Angeles Institute for Metabolic Research

Los Angeles Institute for Metabolic Research Dedicated to improving the lives of people with diabetes, obesity & liver disease through innovative clinical research.

An incredible evening at the Panama MOUNJARO launch event, where Dr. Juan Pablo Frías shared key clinical data and insig...
08/06/2026

An incredible evening at the Panama MOUNJARO launch event, where Dr. Juan Pablo Frías shared key clinical data and insights with more than 350 Panamanian clinicians. Thank you to everyone who joined this important discussion on advancing the management of obesity and T2D.

We are proud to recognize our Medical Director, Dr. Juan Pablo Frías, who served as a Keynote Speaker at yesterday’s lau...
08/05/2026

We are proud to recognize our Medical Director, Dr. Juan Pablo Frías, who served as a Keynote Speaker at yesterday’s launch of MOUNJARO® (tirzepatide) in Panama—the first country in Central America to introduce this important medicine.

Dr. Frías has been involved in the clinical development of tirzepatide since its Phase 2 program began in 2017. He served as first author of the Phase 2 studies published in The Lancet and Diabetes, Obesity and Metabolism in 2018 and subsequently participated in the Phase 3 SURPASS and SURMOUNT programs that supported the approval of tirzepatide for type 2 diabetes as MOUNJARO and for obesity as ZEPBOUND®.

He also served as lead author of the landmark SURPASS-2 trial, published in The New England Journal of Medicine, which compared tirzepatide with semaglutide in people with type 2 diabetes.

In Latin America, Dr. Frías has contributed to MOUNJARO pre-launch and launch activities across Chile, Peru, Argentina, the Dominican Republic, and now Panama.

With more than 25 years of clinical research experience—much of it focused on GLP-1–based therapies—Dr. Frías and the LA-IMR team remain committed to advancing treatments that improve the lives of people living with obesity, diabetes, and metabolic liver disease.

Congratulations, Panama, on this important milestone!

We are proud to share that our Medical Director, Juan Pablo Frías, MD, Adjunct Clinical Professor of Medicine at Charles...
06/24/2026

We are proud to share that our Medical Director, Juan Pablo Frías, MD, Adjunct Clinical Professor of Medicine at Charles R. Drew University of Medicine and Science, recently joined an expert panel on the CGM Education podcast to discuss the real-world management of metabolic dysfunction-associated steatohepatitis (MASH) in people with diabetes: multidisciplinary provider and patient perspectives.

The expert panel was led by Carol H. Wysham, MD, FACP, Clinical Endocrinologist at MultiCare/Rockwood Clinic, Clinical Professor of Medicine at the University of Washington School of Medicine, and Past President of the Endocrine Society.

In addition to Dr. Frias, the panel included Brian Lam, PA-C, Principal and Sub-Investigator for Inova's Hepatology Research, co-chair of the APP committee of the Global NASH/MASH Council and a person living with metabolic liver disease, Inez.

This important discussion highlights the value of multidisciplinary care in improving outcomes for individuals living with diabetes and MASH.

Listen in and learn from these leading voices in metabolic health by scanning the QR code on the flyer or visiting the CGM Education website here: https://cgmeducation.net/webcast/index.php?id=101&load=cast&sub=1

04/28/2026

¿Sabías que la enfermedad del hígado graso no alcohólico ocurre cuando se acumula grasa en el hígado en personas que consumen poco o nada de alcohol? Está relacionada con condiciones como obesidad, resistencia a la insulina, prediabetes y diabetes tipo 2.

La mayoría de las personas no presentan síntomas, por lo que puede pasar desapercibida. Sin embargo, con el tiempo puede avanzar a inflamación, fibrosis (cicatrización del hígado) y enfermedades hepáticas más graves.

¿La buena noticia? Detectarlo a tiempo hace la diferencia.

En nuestro instituto, ofrecemos el FibroScan, un ultrasonido rápido, y no invasivo que mide la grasa y rigidez del hígado para evaluar su salud.

¡Toma el control de tu salud hoy!
Agenda tu cita aquí: https://metabolic.la/schedule-an-appointment

Dr. Frías is attending the Obesity Medicine 2026 Conference in San Diego!This conference brings together top doctors and...
04/10/2026

Dr. Frías is attending the Obesity Medicine 2026 Conference in San Diego!

This conference brings together top doctors and researchers to share the latest advancements in obesity care—from new medications and nutrition strategies to mental health support and innovative technology.

Did you know❓
In Los Angeles County, 1 in 4 adults have obesity, and more than half are either overweight or obese.

That’s why our work at Los Angeles Institute for Metabolic Research matters. We are committed to bringing innovative clinical research opportunities to our local community, helping patients access cutting-edge treatments while contributing to the future of healthcare.

Want to learn more about the work we’re doing at Los Angeles Institute for Metabolic Research? Explore our work: https://metabolic.la/

🚶‍♀️💙 We were proud to be part of the Breakthrough T1D Walk this past Saturday at the Rose Bowl in Pasadena!It was amazi...
03/23/2026

🚶‍♀️💙 We were proud to be part of the Breakthrough T1D Walk this past Saturday at the Rose Bowl in Pasadena!

It was amazing connecting with organization members, everyone who stopped by our booth, and most importantly, the incredible T1D community. Your stories, strength, and support for one another are truly inspiring.

Breakthrough T1D continues to play a critical role in advancing research, advocacy, and progress toward better treatments—and ultimately a cure. We’re honored to support that mission.

At our booth, we shared information about ongoing clinical research at our Institute, including a study evaluating a once-weekly, long-acting insulin for individuals with T1D.

Thank you to everyone who stopped by to speak with us!

If you or someone you know may be interested in participating in clinical research, we welcome you to connect with our team.

We look forward to continuing this work together and we’re already looking forward to next year! 🙌 ✨

Clinical research can serve as a compass, guiding the future of type 2 diabetes (T2D) treatment. A local study is enroll...
03/23/2026

Clinical research can serve as a compass, guiding the future of type 2 diabetes (T2D) treatment. A local study is enrolling adults with T2D and elevated cortisol. Those who qualify will receive:

✅ Study-related medical care at no cost
✅ Regular check-ins with research teams and medical staff
✅ Possible reimbursement for travel + expenses

Learn more: https://metabolic.la/captain-t2d-study-2026.

Steering the journey with type 2 diabetes (T2D) can feel like facing unpredictable tides. A local research study is inve...
03/19/2026

Steering the journey with type 2 diabetes (T2D) can feel like facing unpredictable tides. A local research study is investigating a medication for adults managing T2D. Those who qualify will receive:

✅ Study-related medical care at no cost
✅ Regular check-ins with research teams and medical staff
✅ Possible reimbursement for travel + expenses

Learn more: https://metabolic.la/captain-t2d-study-2026.

Dr. Juan Pablo Frías, Medical Director and Principal Investigator at the Los Angeles Institute for Metabolic Research, p...
03/16/2026

Dr. Juan Pablo Frías, Medical Director and Principal Investigator at the Los Angeles Institute for Metabolic Research, presented 52-week data of icovamenib in people with type 2 diabetes at the 19th International Conference on Advanced Technologies and Treatments for Diabetes (ATTD) in Barcelona, Spain.

Dr. Frías was an invited speaker at the 1st ATTD Congress in Prague in 2008, where he presented on two therapies that were just emerging at the time—the first GLP-1 receptor agonist (exenatide twice daily) and the first amylin analog (pramlintide) for the treatment of diabetes.

From those early GLP-1 and amylin therapies to today’s next generation of metabolic treatments, the field has advanced tremendously.

Over the past two decades, investigators and staff now at the Los Angeles Institute for Metabolic Research have contributed to the clinical development of many important therapies for diabetes, obesity, and metabolic liver disease—and we remain committed to continuing to help advance the field.

The people behind the purpose.Every day, our team shows up with a shared commitment: to improve the lives of people affe...
03/11/2026

The people behind the purpose.

Every day, our team shows up with a shared commitment: to improve the lives of people affected by diabetes, obesity, metabolic liver disease, and related conditions. Through high-quality, community-connected clinical research, we’re working to advance safe and effective therapies that make a real difference.

🔗 Learn more at https://metabolic.la/.

Address

1513 S. Grand Avenue, Suite 320
Los Angeles, CA
90015

Opening Hours

Monday 7am - 3:30pm
Tuesday 7am - 3:30pm
Wednesday 7am - 3:30pm
Thursday 7am - 3:30pm
Friday 7am - 3:30pm

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