Sorrell MD

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Sorrell MD Board-certified internal medicine physician (FACP). Direct-pay, evidence-based precision and longevity medicine. Clinical rigor, not wellness trends.

Telemedicine nationwide; in-person in Southlake, TX by appointment only.

11/09/2026

Feeling foggy or run down mid-day? Sometimes it's your nervous system stuck in "go" mode.

Breath work is one of the simplest ways to shift toward a calmer, parasympathetic state. Box breathing: in for 4, hold for 4, out for 4, hold for 4.

Try a few rounds next time the fog hits.

From my conversation with Dr. Zack Morgan.

11/06/2026

The most common mistake I see at the start: trying to fix everything at once.

All the labs, the full protocol, everything on day one — then burnout, and it all gets dropped.

Pick the top issue and the top goal. Start there. Then build.

From my conversation with Dr. Zack Morgan.

11/04/2026

Why I left insurance-based medicine.

In the traditional model, time and financial constraints often meant I couldn't go as deep as I wanted — on lifestyle, on supplements, on the more advanced diagnostics that can uncover what's really going on.

I built Sorrell MD so I could fully work up every patient, the best that I can.

More on how the practice works: link in bio.

From my conversation with Dr. Zack Morgan.

11/02/2026

Before you get excited about any supplement regimen, gadget or biohack: sleep, stress management, nutrition, exercise.

Those are the foundation. Everything else can be a useful adjunct — but it can't make up for missing fundamentals.

From my conversation with Dr. Zack Morgan.

10/30/2026

Our traditional system is set up to be decent sick care. It isn't really set up to keep healthy people healthy.

What I value about longevity medicine: it gives us tools to look deeper and earlier — like insulin resistance and sensitivity — while there's still time to course-correct.

From my conversation with Dr. Zack Morgan.

10/28/2026

Randomized controlled trials are the gold standard, and they matter.

But the patient sitting in front of you can't always wait 10–20 years for one to be published. They need a decision now — made from all the evidence we have today, weighed honestly.

"No long-term RCT" isn't the same as "no evidence."

From my conversation with Dr. Zack Morgan.

10/26/2026

Longevity medicine isn't about living forever.

It's about the number of healthy, high-function years you get — what researchers call healthspan, not just lifespan.

From my conversation with Dr. Zack Morgan on what "longevity" actually means in practice.

10/22/2026

Your cortisol probably isn’t too high. It’s high at the wrong time.
Cortisol is supposed to peak shortly after you wake up and fall to its lowest point around bedtime. Light hitting your eyes is one of the biggest inputs that sets that daily curve. A flattened curve (low in the morning, elevated at night) is associated with poorer sleep, daytime fatigue, and worse cardiometabolic markers.
Four levers I go through with patients:
☀️ Morning light, in your eyes
Get outside within the first hour of waking. Skip the sunglasses, and don’t stare at the sun. Even overcast daylight is many times brighter than indoor lighting, and it’s the strongest timing signal your circadian clock gets.
🌇 Daylight again later in the day
Getting outside in the afternoon and evening adds to your total daylight exposure. People who get more bright light during the day appear to be less sensitive to light at night. The evidence supports daylight exposure overall, not anything unique about sunset.
🌙 Dim the lights after dark
Bright light at night suppresses melatonin and pushes your clock later. Overall brightness matters more than color. So dim the overhead lights, switch to lamps, and turn your screen brightness down. Night mode helps a little, but it doesn’t make a bright screen fine.
🫁 Box breathing during the day
Inhale 4, hold 4, exhale 4, hold 4. A few minutes of slow breathing reliably lowers your heart rate in the moment. Think of it as a stress-regulation tool. The data on long-term cortisol changes is limited.
If you rank these by evidence, light timing is the heavy hitter, and breathing is a useful tool on top of it.
If you’re doing all of this and still feel flat in the morning and wired at night, that’s worth measuring instead of guessing. A multi-point cortisol curve shows what your rhythm actually looks like.
Dr. Luke Sorrell, MD, FACP | Sorrell MD
Educational content, not medical advice.
preventivemedicine executivehealth boxbreathing

FIB-4 is a non-invasive estimate of advanced liver fibrosis risk. It combines age, AST, ALT and platelet count, routine ...
10/16/2026

FIB-4 is a non-invasive estimate of advanced liver fibrosis risk. It combines age, AST, ALT and platelet count, routine blood values.

It is a triage tool. It helps decide who can stay in primary metabolic follow-up and who needs further testing. The 2026 American Family Physician review of MASLD describes two steps: risk-stratify with FIB-4 first, then elastography, which estimates liver stiffness, when the score is indeterminate or high-risk.

A number from an online calculator misses context: recent illness, alcohol use, other liver diseases, medications and age. Bring it to a physician rather than closing the case yourself.

Confusion, vomiting blood, black stools, severe abdominal pain or sudden jaundice need emergency evaluation, not a calculator.

Full article: sorrell-md.com/blog/fib-4-first-masld

Educational content, not medical advice.

An annual physical produces cholesterol, glucose, blood pressure and weight. All worth knowing, and I look at all of the...
10/15/2026

An annual physical produces cholesterol, glucose, blood pressure and weight. All worth knowing, and I look at all of them. But if I could keep only one measurement to estimate how long and how well someone is likely to live, I would choose cardiorespiratory fitness.

In an analysis of more than 122,000 patients who had treadmill testing, the lowest-fitness group carried risk comparable to smoking, diabetes and coronary artery disease, with no observed point where more fitness stopped helping. In the PURE study of nearly 140,000 adults, each 5 kg drop in grip strength was associated with roughly 16% higher all-cause mortality.

Both are modifiable at any age, and the steepest returns come from moving off the bottom of the distribution. Get a number you can repeat, write down your grip strength, and recheck the trend.

Full article: sorrell-md.com/blog/vo2-max-and-grip-strength-predict-lifespan

Educational content, not medical advice.

Address

1560 E Southlake Boulevard Ste 100
Southlake, TX
76092

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 4pm

Telephone

+18175183467

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