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NEJM Catalyst Practical innovations in health care delivery:

Ideas, solutions, and case studies to improve patient care and drive value in health organizations.

Health care delivery is undergoing a major transformation around quality, cost, and access. NEJM Catalyst brings health care executives, clinician leaders, and clinicians together to share innovative ideas and practical applications for enhancing the value of health care delivery. NEJM Catalyst brings insightful articles and real-life examples from a network of top thought leaders, experts and advisors to provide:

Practical innovations in health care delivery;

Impeccable quality and impact;

Active contributions from renowned authorities, thought-leaders, and advisors;

Independent and impartial curation; and

An exchange of ideas among executives and clinicians. NEJM Catalyst is produced by NEJM Group, a division of the Massachusetts Medical Society, located in Waltham, Massachusetts.

AGE-FRIENDLY HEALTH SYSTEMS 4MS THEME ISSUE: A survey of the NEJM Catalyst Insights Council finds that the 4Ms — What Ma...
10/31/2026

AGE-FRIENDLY HEALTH SYSTEMS 4MS THEME ISSUE: A survey of the NEJM Catalyst Insights Council finds that the 4Ms — What Matters, Medication, Mentation, and Mobility — are used globally to care for aging adults.

The Age-Friendly Health Systems (AFHS) movement has advanced adoption of the 4Ms (What Matters, Medication, Mentation, a...
10/30/2026

The Age-Friendly Health Systems (AFHS) movement has advanced adoption of the 4Ms (What Matters, Medication, Mentation, and Mobility) framework, but health systems need evidence of whether or not adherence is associated with outcomes.

The authors of a new article describe an effort that adapted and implemented previously developed electronic health record (EHR)–based 4Ms measures at a large academic medical center. In a retrospective cross-sectional analysis, the authors measured encounter-level adherence to 4Ms care for patients 65 years of age and older hospitalized for more than 24 hours between December 2022 and May 2025. The authors evaluated the association of 100% encounter-level adherence to 4Ms assessments plus proportions of nursing shifts with 100% of 4Ms actions taken with length of stay (LOS) and odds of discharge to a postacute care (PAC) facility.

The study sample included 12,905 unique patients who had 20,512 inpatient encounters. Of those, 36.6% met 100% adherence to the Assessment components of the 4Ms. Only 8.4% of encounters had 100% adherence to 4Ms Assessment components plus complete adherence to 4Ms Act-On components for 25% of an encounter; 2.8% had 100% Assessment adherence plus complete adherence to 4Ms Act-On components for 50% of an encounter; and 0.4% had 100% Assessment adherence plus complete adherence to 4Ms Act-On components for 75% of an encounter. Greater 4Ms adherence was associated with lower postacute facility discharge across the first three adherence thresholds and shorter LOS across all thresholds, with LOS reductions increasing from 1.4 days at Assessment plus 25% Act-On to 2.9 days at Assessment plus 75% Act-On.

These findings suggest that EHR-based 4Ms measurement by AFHS-recognized organizations can help those systems target workflow improvements to support outcome-oriented care delivery for older adults.

Industrialization, urbanization, population growth, and lifestyle changes have collectively contributed to a growing glo...
10/29/2026

Industrialization, urbanization, population growth, and lifestyle changes have collectively contributed to a growing global burden of gynecologic diseases. These factors have adversely affected women’s reproductive health and overall quality of life, with repercussions that extend to their families and wider communities.

In China, county-level public hospitals serve as the primary providers of care or first line of defense for managing these conditions, highlighting the urgent need for improved service quality. However, a systematic framework with specific quality indicators for gynecologic care remains underdeveloped both in China and internationally. Compared with obstetrics, progress in gynecologic care quality assessment has lagged, creating a gap between evidence and practice.

To close this gap, the authors established mainland China’s first validated indicator system for gynecologic care quality. National implementation across 178 hospitals demonstrates the framework’s practical utility while revealing significant quality differences across hospital tiers and regions. This standardized evaluation framework provides a practical tool for targeted quality assessment and precision improvement in primary gynecologic care.

AGE-FRIENDLY HEALTH SYSTEMS 4MS THEME ISSUE:Early testing of a survey instrument designed to capture systemwide status o...
10/28/2026

AGE-FRIENDLY HEALTH SYSTEMS 4MS THEME ISSUE:

Early testing of a survey instrument designed to capture systemwide status of Age-Friendly Health System implementation reveals challenges and opportunities in generating a singular continuous measure of progress that can support implementation and outcomes research at scale.

Commentary: A three-tier operational model for the U.S. Centers for Medicare and Medicaid Services age-friendly measure,...
10/27/2026

Commentary: A three-tier operational model for the U.S. Centers for Medicare and Medicaid Services age-friendly measure, for the efficient deployment of geriatric expertise according to patient need, while supporting the implementation of universal age-friendly practices and providing care escalation pathways for high-risk patients with frailty and multicomplexity.

A framework developed by both VA and non-VA multidisciplinary leaders offers a roadmap for health care systems to suppor...
10/26/2026

A framework developed by both VA and non-VA multidisciplinary leaders offers a roadmap for health care systems to support the design and implementation of a sustainable, evidence-driven care model to support older patients across the full continuum of care with particular attention to the 4Ms model. Learn more: https://nej.md/4yzBMQC

An initiative at Jefferson Health involving 5234 provisioned clinicians and more than 283,000 ambulatory encounters has ...
10/24/2026

An initiative at Jefferson Health involving 5234 provisioned clinicians and more than 283,000 ambulatory encounters has been associated with reduced time spent and effort expended in documenting patient encounters, with benefits concentrated among the most documentation-burdened clinicians, particularly advanced practice clinicians.

From January 2022 to June 2025, a cohort-based implementation model used to integrate 4Ms care delivery was associated w...
10/23/2026

From January 2022 to June 2025, a cohort-based implementation model used to integrate 4Ms care delivery was associated with improvement in certain clinical outcomes, while the long-term systemwide stretch goal of 95% adherence with all 4Ms has remained unmet at 45%.

A review of 40,411 inpatient encounters at Houston Methodist among adults 70 years of age or older found that only 3% of...
10/22/2026

A review of 40,411 inpatient encounters at Houston Methodist among adults 70 years of age or older found that only 3% of encounters achieved higher-level compliance with 4Ms (What Matters Most, Medication, Mentation, and Mobility) care documentation; however, that subgroup was associated with shorter length of stay and reduced unplanned 30-day readmissions.

The articles in our special issue on Age-Friendly Health Systems highlight important benefits realized from AFHS impleme...
10/21/2026

The articles in our special issue on Age-Friendly Health Systems highlight important benefits realized from AFHS implementation efforts to date and challenges that are critical to address for the movement to fully deliver on its goals. Guest editor Julia Adler-Milstein summarizes what you'll find inside: https://nej.md/4jvMFyS
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