Agency for Care Effectiveness - ACE

Agency for Care Effectiveness - ACE ACE is the national health technology assessment (HTA) and clinical guidance agency in Singapore. What We Do


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Welcome to the official page of the Agency for Care Effectiveness (ACE). Established by the Ministry of Health, the Agency for Care Effectiveness (ACE) is the national Health Technology Assessment (HTA) and Clinical Guidance Agency in Singapore. We support providers, patients, and payers make better-informed decisions about patient care. We achieve this by conducting health technology ass

essments (HTAs), publishing healthcare guidances and providing education. HTA

Established by the Ministry of Health in 2015, we are the national HTA agency in Singapore. We conduct technical evaluations that inform funding decisions for health technologies, and drive their appropriate use by:

• Publishing technology guidances on the clinical effectiveness, safety, and cost-effectiveness of health technologies;
• Conducting value-based pricing negotiations with manufacturers to ensure that prices of patented health technologies are commensurate with the outcomes they deliver for patients and the Singapore health system;
• Tracking utilisation and outcomes related to funded health technologies to study the impact of funding decisions;
• Developing and implementing adoption strategies within public healthcare institutions to drive uptake of technology guidances. Clinical Guidance

We develop and publish clinical guidances that provide concise, evidence-based recommendations to inform specific areas of clinical practice. Healthcare Professional Education

We assist healthcare professionals to apply the best available evidence in their practice through collaborative continuing professional education. Healthcare Consumer Education

We provide information and tools for patients and caregivers to help them find out more about different medical conditions and treatment options, and to take part in shared decision-making with their clinicians about their healthcare needs. Find out more about our work at https://www.ace-hta.gov.sg/campaign/

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Social Media Terms of Use

We encourage all visitors on our page to start conversations and share with us your thoughts, suggestions, and comments, if any. While we welcome constructive discussions, and want everyone’s experience to be positive, please note that any offensive posts or comments will be removed, and users that repeatedly breach the terms of use may also be blocked from this page. As social media is not a platform for clinical advice – please get in touch with your pharmacist or doctor regarding medical queries. Out of respect for users of our page, ACE reserves the right to remove any comments or posts of the following nature:
- Abusive, vulgar, obscene, violent or defamatory language
- Hateful or discriminatory remarks towards any specific groups or individuals
- Advertising, promotion or endorsement of any products, services or brands
- Fraudulent, inaccurate, non-evidence based information, including spam
- Violation of any copyright, contains proprietary or personal information (email addresses, phone numbers, account numbers etc.)
- Any other comments or posts that breach Facebook’s Term of Service of Community Standards.

28/07/2026

World Hepatitis Day highlights the importance of raising awareness on hepatitis testing, treatment and care.

In Singapore, chronic hepatitis C affects around 12,000 people, many of whom may not experience symptoms until serious liver complications develop.

Through health technology assessment, ACE supports informed decision-making on clinically and cost-effective treatments, helping healthcare professionals deliver care that is grounded in evidence and value. Sofosbuvir and velpatasvir are direct-acting antivirals (DAAs) that are included on the MOH List of Subsidised Drugs for treating chronic hepatitis C.

Visit us at www.ace-hta.gov.sg

08/07/2026

Have you ever come across a healthcare-related term in our educational resources that you were unfamiliar with?

Our updated Patient Glossary provides simple definitions to help patients and carers better understand technical terms commonly used in ACE’s work. 📖

Find out more here: https://go.gov.sg/acefb321

ACE and the Health Sciences Authority (HSA) have jointly developed a patient factsheet on biosimilars - and there's a lo...
30/06/2026

ACE and the Health Sciences Authority (HSA) have jointly developed a patient factsheet on biosimilars - and there's a lot to know!

Did you know that biosimilars are safe and effective medicines that have been used around the world for almost 20 years to treat a wide range of conditions?

In Singapore, selected biosimilars are subsidised as they provide the same therapeutic benefits as the reference biologics while offering good value for money, making them more affordable.

Learn more about biosimilars and the subsidised options available here: https://go.gov.sg/acefb320

12/06/2026

On 13 May 2026, ACE's Consumer Engagement and Education (CEE) team welcomed Consumer Panel members as they begin a new term, during a productive meeting focused on strengthening patient involvement in healthcare decision-making.

Together, we discussed how the Panel can play a greater role in ACE's work including strengthening patient involvement across ACE’s activities, enhancing stakeholder understanding of ACE’s role, maximising the reach and impact of our consumer education efforts, and demonstrating the Panel's influence on healthcare decision-making in Singapore.

A big thank you to all Panel members for your valuable insights and thoughtful suggestions. We look forward to continuing our collaboration to further strengthen patient involvement in health technology assessment (HTA) in Singapore!

Interested in getting more involved in ACE's work? Find out more here: https://go.gov.sg/acefb318

11/06/2026

ACE was proud to present at a workshop hosted by the Centre for Innovation in Regulatory Science, held from 3-5 March in Kuala Lumpur! The workshop brought together stakeholders from regulatory agencies, HTA bodies, industry and patient organisations to explore how to build capacity for patient involvement in regulatory and HTA decision-making across the Asia-Pacific region.

Valuable insights were shared during the workshop – Senior Advisor Fiona Pearce presented on global versus Asia-Pacific patient involvement practices, drawing from recent HTAi 360 studies, while Senior Specialist Mr Shawn Quek discussed approaches to building capacity for patient involvement in Singapore's HTA process.

We congratulate CIRS on delivering such an informative session and look forward to future workshops.

👉 Interested in getting involved? Find out more about patient involvement opportunities in Singapore: https://go.gov.sg/acefb317

11/06/2026

In a health technology assessment (HTA), the PICO framework, which stands for Population, Intervention, Comparison, and Outcome, is used to define the research question that the HTA aims to answer. It also helps develop clear search terms to find the best available evidence to inform the assessment.

🔍 Learn more about the PICO framework in our new learning module: go.gov.sg/acefb314

06/06/2026

Did you know that around 3 in 10 adults have moderate-to-severe obstructive sleep apnoea (OSA)? Many people don't realise they have it as it is often mistaken for "normal" snoring.

For people with moderate-to-severe OSA, positive airway pressure (PAP) devices can help keep the airway open during sleep, improving breathing and sleep quality. In Singapore, eligible patients may receive a one-time subsidy for these devices.

Learn more about OSA and PAP devices from our patient factsheet: https://go.gov.sg/acefb312

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College Of Medicine Building, 16 College Road
Singapore
169854

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